DRUGS for THE BRAIN from THE BRAIN: Neuropeptides as Leads for CNS Pharmaceuticals

Seminar Center for Excellence in the Neurosciences Seminar Series

Robin Polt, Ph.D.

Professor of Chemistry and Associate Professor of Medical Pharmacology, University of Arizona

Hosted by: Edward Bilsky, Ph.D.

Biography

Robin Polt, Ph.D. is in the Department of Chemistry and Biochemistry at the University of Arizona. Dr. Polt earned his BS from Indiana University-Purdue Universitity Indianapolis in 1981 and his Ph.D. from Columbia University in 1986. He completed a postdoctoral fellowship at ETH in Zurich, Switzerland. Dr. Polt has research interests in the following areas: organic and biological chemistry, bioorganic and natural products, synthesis and synthetic methodiology, organometalilic and coordination chemistry and pharmacology and toxicology.

New synthetic methodology developed in the “Polt Group” is focused on the use of metal-ligand interactions to direct C-C and C-O bond formations starting from amino acids, such as L-alanine and D-serine. These new methods are being applied to the synthesis of highly-functionalized natural products such as castanospermine which functions as a glycosidase inhibitor, or to unnatural substrate analogues designed to inhibit glycoprotein processing enzymes (glycosyltransferases). Dr. Polt’s laboratory has collaborated with Dr. Bilsky’s laboratory at the University of New England testing these novel compounds for their therapeutic effects on acute and chronic pain states.

Over his 25 years as a chemist Dr. Polt has many peer reviewed publications, book reviews, and numerous book chapters published.

Sponsors

Center for Excellence in Neurosciences

Contact

cen@une.edu

Sep292011
12:00 PM
Alfond Room 106

Biddeford Campus

Free and open to the public