University of New England

Mark Andrew Sweezy
Assistant Professor of Chemistry (Biochemistry)
msweezy@une.edu

EDUCATION
The University of Vermont, Burlington
Department of Microbiology and Molecular Genetics, Ph.D., 1998
Advisor: Dr. Scott W. Morrical
Dissertation title: The Role of the uvsY Protein in the Assembly of a    Presynaptic Filament in Bacteriophage T4

Western State College of Colorado, Gunnison
Department of Biology, B.A.,1989

PROFESSIONAL EXPERIENCE

Teaching Experience
University of New England, Department of Chemistry and Physics
¨Developed lectures and laboratories for chemistry courses. 2002- present
Developed and implemented curriculum for lecture and laboratory courses in General Chemistry, Introductory Chemistry, Biochemistry and Principles of Biochemistry .

University of Vermont, Department of Microbiology and Molecular Genetics and University of Colorado, Department of Molecular, Cellular and Developmental Biology
¨Instructed undergraduate research projects on an individual basis, 1995-2002

University of Colorado, Department of Molecular, Cellular and Developmental Biology
¨Lectures in MCD3510: Biology of the Cancer Cell, 2000-2002 

University of Vermont, Department of Microbiology and Molecular Genetics
¨Lectures in BIOC310: Proteins and Nucleic Acids, 1997-1998
¨Course Development, 1992-1993
Worked with two faculty members to develop and implement a course in molecular cloning 
¨Teaching Assistant, 1992-1993
MMG201: Molecular Cloning Laboratory
MMG222: Clinical Microbiology
Western State College of Colorado
¨Teaching Assistant, 1986-1989

Departments of Chemistry and Biology
Research Experience
University of New England, Department of Chemistry and Physics
¨Principle Investigator in DNA Recombination and Repair, 2002-present
Trained students and conducted research in the molecular mechanism and  structural biology of DNA repair in Schizosaccharomyces pombe.

University of Colorado, Department of Molecular, Cellular and Developmental Biology
¨Postdoctoral Research Associate, 1999-2002
Laboratory of Dr. J. Richard McIntosh
Cytological and biochemical research on the role of Kinesin-like protein 2 of S. pombe in mitosis.

University of Vermont, Department of Microbiology and Molecular Genetics
¨Graduate Student, 1994-1999
 Laboratory of Dr. Scott W. Morrical
Conducted physical biochemical research on the assembly of a functional presynaptic filament in bacteriophage T4.
¨Graduate Student, 1992-1994
 Laboratory of Dr. Richard A. Fishel
Conducted biochemical and cytological research on the role of RP-A in replication, recombination and cell cycle progression in human systems.

Associates of Cape Cod, 1989-1991
¨Research Associate
 Department of Research and Development
Purification and characterization of the lipid-A binding properties of ENP, an endotoxin binding protein of Limulus sp.
The development of process scale purification procedures and initialization of GMP protocols for the purification of ENP.

The University of Colorado, Boulder, 1988
¨Summer Research Assistant
 Laboratory of Dr. Marvin Carruthers
Assisted in the purification and characterization of SF-1, an essential factor for in vitro RNA splicing reactions.

Military Experience
The United States Army, 1980-1983
¨Basic Medical Specialist
Served in the emergency, critical care and obstetrics wards of Madigan Army Medical Center.  Served as non-commissioned officer in charge of an STD clinic. Assisted in the establishment of a combat ready medical team as a member of the ranger support element of the 75th Rangers.

GRANTS AND FELLOWSHIPS

University of New England Faculty Development Award, 2003-2005

University of New England College of Arts and Sciences Award, 2003-2005

National Science Foundation Minority Postdoctoral Research Fellowship, 1999-2002

National Science Foundation Minority Graduate Research Fellowship, 1992-1996

University of Vermont Travel Grant, 1996

Western State College Academic Scholarship, 1988

SERVICE ON COMMITTEES

UFA Academic Affairs Committee, 2005- present

CAS Academic Curriculum Committee, 2002-present

Co-chair CAS Academic Curriculum Committee, 2003-2005

CAS Core Curriculum Committee, 2003-present

Student Awards Committee, 2002-2005

HONORS AND AWARDS

Finalist for the Debra Summers Teaching Award, 2003-2005

National Academy of Natural Sciences Award, 1987

Scholastic All American, 1987

US Army Expert Field Medical Badge, 1981

PUBLICATIONS

Sweezy, M.A. and Fishel, R. (1994)  Multiple Pathways Leading to Genome Instability and Tumorigenesis. Annals of the New York Academy of Sciences 726, (165-177).

Sweezy, M.A. and Morrical, S.W. (1997) Single-stranded DNA Binding Properties of the uvsY Recombination Protein of Bacteriophage T4. J. Mol. Biol . 266, ( 927-938).

Sweezy, M.A. and Morrical, S.W. (1998) Biochemical Interactions Within a Ternary Complex of the Bacteriophage T4 Recombination Proteins gp32 and uvsY Bound to ssDNA. Biochemistry, 37, (5673-5681).

Troxell, C.T., Sweezy, M.A., West, R.R., Reed,K.D., Carson, B.D., Pidoux, A.L., Cande, W.Z. and McIntosh, J. R.(2001) pkl1+ and klp2+: two kinesins of the KAR3 subfamily in fission yeast that perform different functions in both mitosis and meiosis Mol. Biol. Cell, 12 (3476-3488).

RECENT PRESENTATIONS

Hirschhorn, M; Green, D and Sweezy, MA (2005) Cloning and characterizationof the RAD51 gene of Schizosaccharomyces pombe.  Maine Biological & Medical Sciences Symposium, Bar Harbor, ME

Gerrish, AM and Sweezy, MA (2005) Cloning and expression of the RAD54 gene of Schizosaccharomyces pombe.  Maine Biological & Medical Sciences Symposium, Bar Harbor, ME

Manahl, M and Sweezy, MA (2005) Cloning and expression of the RAD22 gene of Schizosaccharomyces pombe.  Maine Biological & Medical Sciences Symposium, Bar Harbor, ME