University of New England

Faculty Profile:                 
Glenn W. Stevenson



Assistant Professor
207-602-2285
gstevenson@une.edu

Education
Postdoctoral Fellowship: McLean Hospital-Harvard Medical School
Ph.D.: American University, Behavioral Neuroscience
M.A.: American University, Psychology
B.A.: Muhlenberg College, Psychology
 
Courses
Psy 275 - Intro to Psychobio Methods & Techniques
Psy 365 - Biological Bases of Behavior
Psy 380 - Learning and Memory
 
Research Interests

• Psychopharmacology of acute and chronic pain, and drug addiction
• Development of reliable and predictive preclinical models of pain and analgesia that capture clinically important aspects of chronic pain.
• Evaluation of mu, delta and kappa opioid drug combinations using a broad range of preclinical assays that measure clinically useful effects (e.g. analgesia), and undesirable side effects (e.g. respiratory depression, drug dependence), with the goal of determining optimum therapeutic ratios for the development of new drugs or drug mixtures with improved efficacy and safety.

Research Grants

National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIAMS, NIH) AREA grant. Funding cycle: 2007-2010. This grant is funding research on exploration of new preclinical strategies for assessing chronic pain and assessing analgesic drugs in rodents. It is predicted that development of these models will facilitate development of more effective and safer drugs to treat pain in human and veterinary populations.

Selected Publications

Stevenson, G.W., Bilsky, E.J., Negus, S.S. Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: Effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice. The Journal of Pain, 7(6):408-416; 2006.

Stevenson, G.W., Folk, J.E., Rice, K.C., Negus, S.S. Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: Studies with SNC80 and heroin. The Journal of Pharmacology and Experimental Therapeutics, 314:221-231; 2005.

Stevenson, G.W., Bidlack, J.M., Wentland, M.P., Mello, N.K., Negus, S.S. Effects of the mixed-action k/m opioid agonist 8-CAC on cocaine- and food-maintained responding in rhesus monkeys. European Journal of Pharmacology, 506(2):133-141; 2004.

Stevenson, G.W., Folk, J.E., Linsenmayer, D.C., Rice, K.C., Negus, S.S. Opioid interactions in rhesus monkeys: Effects of d + m and d + k agonists on schedule-controlled responding and thermal nociception. The Journal of Pharmacology and Experimental Therapeutics, 307:1054-1064; 2003.

Stevenson, G.W., Canadas, F., Ullrich, T., Rice, K.C., Riley, A.L. SNC80 discriminative control is mediated by the delta receptor: assessment of delta opioid substitution and antagonism. Pharmacology, Biochemistry and Behavior, 71(1-2):283-292; 2002.

Stevenson, G.W., Canadas, F., Zhang, X., Rice, K.C., Riley, A.L. Morphine discriminative control is mediated by the mu opioid receptor: assessment of delta opioid substitution and antagonism. Pharmacology, Biochemistry and Behavior, 66:851-856; 2000.

Stevenson, G.W., Pournaghash, S., Riley, A.L. Antagonism of drug discrimination learning with the conditioned taste aversion procedure. Pharmacology, Biochemistry and Behavior, 41:245-249; 1992.