Research News
Ann Cowles and Marilyn Gugliucci win Maine Fitness Award for U-ExCEL Balancing Act
The Governor’s Council on Physical Activity, which bestowed the award, has invited Cowles and Gugliucci to a celebration at the State House Hall of Flags in Augusta on June 6th.
Posted on: 5/02/2012
Polly Leonard presents poster and gives presentation at NAOME annual meeting
Associate Clinical Professor, UNECOM, Dr. Polly Leonard (UNECOM ’96, MMEL ’11) recently attended the 2012 Annual Meeting of the National Association of Osteopathic Medical Educators (NAOME), in Washington, D.C., where she presented a poster and gave a presentation. The poster was titled “Impediments and Motivators to Nurse Participation in Graduate Medical Education,” and the presentation was titled “Using Dashboard to Manage Clinical Projects.”
Dr. Leonard is the President-Elect of the Northeast Osteopathic Medical Education Network (OPTI) and was recently named a Fellow of the National Academy of Osteopathic Medical Educators (NAOME).
Posted on: 4/12/2012
COM/CEN faculty member Geoffrey Bove speaks at the 3rd Fascia Research Congress
Geoffrey Bove, D.C. Ph.D., associate research professor, Department of Biomedical Sciences, College of Osteopathic Medicine, served as chair of the science committee at the 3rd Fascia Research Congress, which was held in Vancouver B.C., on March 28-30, 2012. This congress focuses on the importance of fascia, the coverings of various organs and tissues, on musculoskeletal health. As chair, Bove facilitated the design of the program and participated in the congress.
On the opening day, besides participating in the opening ceremonies, Bove conducted a plenary panel discussing scars and adhesions. This panel consisted of two surgeons, a naturopath, and a massage therapist (Susan Chapelle, RMT, a collaborator with Bove at UNECOM). Also during the congress, Chapelle presented her’s and Bove’s research on the manual treatment of postoperative adhesions and ileus.
In the final panel of the Congress, Art & Science/Research & Practice, Bove discussed strategies to forge productive collaborations between scientists and clinicians. He was called to the podium during the closing ceremonies for special recognition for his hard work over the last 18 months in preparation for this congress.
On Saturday, March 31st, Chapelle and Bove gave a full day workshop on manual treatment of scars and adhesions to 40 students. The 4th Fascia Research Congress will be hosted in 2015 by the American Osteopathic Associaion. More information.
Posted on: 4/06/2012
David Mokler’s review of opioid drugs to appear in Pain Research and Treatment journal
The journal Pain Research and Treatment has recently accepted a paper by David Mokler, Ph.D., professor of pharmacology in the Department of Biomedical Sciences in the College of Osteopathic Medicine.
The paper, titled, 'Effects of Combined Opioids on Pain and Mood in Mammals,' reviews the use of two classes of opioid (morphine-like) drugs to enhance the effects of each drug to reduce pain while also reducing the side-effects associated with each class of drugs. It is co-authored by Dr. Mokler's doctoral research advisor Richard Rech, Ph.D., Professor Emeritus at Michigan State University, and Shannon Briggs, Ph.D.
The journal, Pain Research and Treatment, is an open access journal; the paper may be downloaded here.
Posted on: 3/26/2012
Marilyn Gugliucci and Kira Rodriguez complete first statewide needs assessment of Maine's older adults
Marilyn R. Gugliucci, Ph.D., Department of Geriatric Medicine, Kira Rodriguez, M.H.S., Research Associate at UNE's Center for Community and Public Health, and Shirl A. Weaver, Ph.D. (Consultant) completed Maine's first statewide assessment on aging funded by the Maine Office of Elder Services in conjunction with the Maine Association of Area Agencies on Aging (M4A).
The 100-page report addressed the question, 'What do Maine's older adults need to remain in their homes?' It includes results from statewide focus groups (Gugliucci/Weaver) and Caregiver/Service Provider Surveys (Rodriguez). The report was presented by Dr. Gugliucci to state leaders in the field of aging.
Directors and executive directors from the Office of Elder Services, Maine Hospice Foundation, Adult Protective Services, Volunteers of America, Maine Health Care Association, Home Care of Maine, Maine Alzheimers Association, Maine Ombudsman Program, Maine Retirees Association, Maine AARP, Maine Legal Services for the Elderly, and Gould Services of Maine participated in the discussion following the presentation to identify next steps in creating the strategic plan to address aging in Maine, a report that is required by the Administration on Aging in order for Maine to access Older Americans Act funding.
The Maine DHHS has past strategic plans that focused on aging issues based on secondary data sources. This is the first time the state conducted a needs assessment with older adults, caregivers for older adults, and service providers for older adults. The needs assessment will be available on the Office of Elder Services and M4A websites in April, with the final strategic plan available in July 2012.
Posted on: 3/20/2012
Nananda Col published in BMC Women’s Health
Nananda Col, M.D., MPP, MPH, a professor of medicine in the University of New England’s College of Osteopathic Medicine, is a senior author of an article in BMC Women’s Health. The article, titled “Factors associated with treatment of women with osteoporosis or osteopenia from a national survey,” explores why so many women are either over- treated or under-treated for osteoporosis.
Osteoporosis is a major public health problem that affects most older women and often results in hip, arm, and spine fractures, including the 'Dowager's hump' and shrinking in height that is falsely understood as an inevitable consequence of old age. These fractures can have a catastrophic effect, often leading to permanent disability, loss of independence, and even death.
Dr. Col states that there are several effective treatments to prevent broken bones from osteoporosis, but the treatments are not making an impact because of the Goldilocks Effect. This term is coined based on the principles that the drugs are used too often by people who receive minimal benefit from them, and too little by those who could greatly benefit from their use. This study explores factors associated with the use of these drugs in the real world, comparing actual use to how they should ideally be used.
The article can be viewed on the BMC Women’s Health website.
Posted on: 3/15/2012
Marilyn Gugliucci presents at national geriatrics conference
Marilyn R. Gugliucci, Ph.D, Department of Geriatric Medicine, presented in five conference symposia at the National Association for Gerontology/Geriatrics in Higher Education (AGHE) Conference in Alexandra Va, Feb. 23-26, 2012. The Conference theme was Engaging Aging in Higher Education. The presentations were entitled:
- AGHE Fellows Mentor Program: Engaging Aging through Relationships, McMullen, T. (Student), Brown, C. (Student), & Gugliucci, M. (AGHE Fellow)
- Partners for Education in Gerontology (PEG): An Innovative Nurse Faculty Development Program. Dr Gugliucci was the keynote for the second session of this symposium. Session organizer: Robin E. Remsburg, George Mason University School of Nursing.
- AGHE Past Presidents Symposium, organized by Dr. Marilyn Gugliucci was entitled: The Presidents "Counsel": Leadership in the Field of Aging. Five AGHE Past Presidents (Sterns, H., Univ of Ohio; Bernard, M., NIA; Kunkel, S., Miami Univ; Rizza, C. Slippery Rock Univ Emeritus, and Gugliucci, M, UNECOM) provided leadership insights applicable to the field of aging.
- Mentorship Toolkit: Complete with Set of Wings was the title of Dr. Gugliucci's presentation for the Hiram J. Friedsam Mentorship Award Session.
- Learning by Living: Architect's View of Living as a Nursing Home Elder Gugliucci, M and Carroll, E, Symposium.
Posted on: 3/08/2012
COM/CEN faculty member Nananda Col to participate in ASCO Breast Cancer Risk Reduction Guideline Panel
Nananda Col, M.D., M.P.H., professor of medicine at the University of New England's College of Osteopathic Medicine and faculty member in the Center for Excellence in the Neurosciences, has accepted an invitation from the American Society of Clinical Oncology (ASCO) to serve on a Breast Cancer Risk Reduction Guideline Panel. Participants were chosen based on their significant contributions or research to the field of oncology, specifically specializing in breast cancer.
The ASCO is a professional oncology society committed to conquering cancer through research, education, prevention and delivery of high-quality patient care. The guidelines these panels discuss address specific clinical situations (disease-oriented) or use of approved medical products, procedures, or tests (modality-oriented). Using the best available evidence, ASCO expert panels identify and develop practice recommendations for specific areas of cancer care that would benefit from using practice guidelines. The criteria for selecting topics for guidelines includes significance of clinical importance; presence of variations in patterns of, or access to care; availability of suitable data; and ethical considerations.
Prior to her involvement with UNE, Dr. Col served as a faculty member at Tufts, Brown, and Harvard Medical Schools. She also served as the principal investigator on numerous federally funded research and training projects that worked to develop web-based shared decision making interventions.
Posted on: 2/17/2012
Nananda Col authors chapter on decision science to enhance patient involvement
Nananda Col, M.D., MPP, MPH, a professor of medicine in the University of New England’s College of Osteopathic Medicine, has been selected as a contributor for, Pharmacoinformatics and Drug Discovery Technologies: Theories and Applications, a book discussing the benefits of using information systems and technology as decision support tools for improved drug management.
As an expert in how patients and health care providers make decisions and communicate about health risks, her chapter is entitled “New Technologies in Personalized Decision Support to Enhance Patient Choice: Applications and Challenges.” It addresses the rapid growth in personalized decision support tools (often available on health web sites) that profess to help patients and/or providers make better decisions about preventing, managing, or treating disease by taking into consideration specific aspects of an individual patient that distinguish them from an 'average' patient. The chapter focuses on the potential and pitfalls of these various approaches, how well they perform, and whether they improve patient outcomes.
The book is scheduled for release in March 2012.
Posted on: 2/13/2012
COM/CEN faculty member Colin Willis has book chapter published
Colin Willis, Ph.D., assistant professor of Biomedical Sciences in COM and a faculty member in the Center for Excellence in the Neurosciences (CEN), has a book chapter published in the series Methods in Molecular Biology “Astrocytes: Methods and Protocols." The chapter, entitled “Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier” describes the methods and protocols used in in vivo imaging. Dr. Willis has been working on these techniques for a number of years at the University of Arizona before he joined the UNE Community in the summer of 2010. Since then he has made great steps at getting his research projects up and running and has obtained funding through 1) the American Heart Association to determine the role intracellular signaling pathways play in modifying blood-brain barrier integrity under hypoxic and post-hypoxic stress and 2) the Migraine Research Foundation to study mechanisms of blood-brain barrier dysfunction induced by overuse of migraine medication.
Citation: Willis CL. Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier. Methods Mol Biol. 2012;814:515-29. PubMed PMID: 22144329.
Posted on: 2/07/2012
COM/CEN faculty members Robert Lenox and Frank Porreca chair a panel discussion on novel pain therapeutics
Robert Lenox, MD, Professor of Pharmacology and Clinical Neurosciences, and Frank Porreca, PhD, Professor of Pharmacology, both affiliated with the University of New England’s College of Osteopathic Medicine and members of the Center for Excellence in the Neurosciences, recently returned from the American College of Neuropsychopharmacology 50th Annual Meeting in December 2011. As part of the scientific program for the meeting, they chaired a major symposium entitled: “The Development of Novel Pain Therapeutics: New Strategies to Overcome Drug Discovery Barriers”. Dr. Porreca presented “Identifying Mechanisms Underlying Affective Components of Pain and Pain Relief in rodents to Promote Discovery of New Therapies” and Dr. Lenox served as Discussant for the symposium. The other speakers in the Panel included Dr. David Borsook, Harvard University; Dr. Irene Tracey, Oxford University; and Dr. Chas Bountra, Oxford University.
A brief abstract of the Panel can be found below:
“New medications have not emerged for the treatment of pain for three reasons: 1) We are unable to preclinically validate mechanistic hypotheses and targets resulting in a lack of translation to humans. 2) We lack understanding of mechanisms that drive pain clinically resulting in an inability to match new mechanisms to appropriate patient groups. 3) The pharmaceutical industry continues to compete on targets without validation, resulting in a lack of collective learning and waste of time and global resources. This ACNP panel consisting of leaders in the field will address scientific strategies including preclinical study of pain perception rather than nocioception; and neuroimaging to identify circuits in animals and humans that modulate the human pain experience to redefine appropriate outcome measures for more effective clinical development. We will also describe the use of structural genomics to produce novel probes for target validation within a public private consortium. Surmounting these drug discovery challenges in pain will provide new insight for the development of novel treatments for other neuropsychiatric disorders.”
Posted on: 1/06/2012
Marilyn Gugliucci featured speaker at NH Abuse Prevention Conference
Marilyn R. Gugliucci, Ph.D. was a featured speaker, along with William Thomas, M.D. (internationally known geriatrician credited with creating the Eden Alternative, Green Houses and Elder Friendly Emergency Rooms), at the State of New Hampshire Abuse Prevention Conference on Nov.10th, 2011 in Lebanon, N.H.
Dr. Gugliucci provided the keynote address for the Conference entitled: Learning by Living: Life Altering Challenges and Concepts in Aging. She also provided an afternoon workshop on Sex and Aging for Nursing Home Administrators, Ombudsmen and Surveyors. Dr. Thomas was the luncheon speaker addressing Risk in Nursing Homes and provided a workshop on Surplus Safety. The conference had 300 plus attendees and was organized by the State of New Hampshire Bureau of Elder and Adult Services and the Office of the Long Term Care Ombudsman.
Posted on: 11/20/2011
Marilyn Gugliucci presents Learning by Living program at Maine Culture Change Coalition
Marilyn R. Gugliucci, Ph.D. director of geriatric research, College of Osteopathic Medicine, provided the education session at the Maine Culture Change Coalition - Local Area Network of Excellence (LANE) meeting in Damariscotta, Maine on Monday, November 7, 2011.
She presented on the Learning by Living Research Project which has been recognized as culture changing research. Evan Carroll, architect and president of Bild Architectural. Inc., presented with Dr. Gugliucci sharing his experiences of living in the Maine Veterans Home, Scarborough during September 2011. Carroll's accounts proved to be quite powerful for this group of health care providers.
Posted on: 11/10/2011
UNE staff member Denise Giuvelis presents poster at AALAS National Meeting
Denise Giuvelis, B.S., a senior research associate in the Bilsky Laboratory, presented a poster at the American Association for Laboratory Animal Science (AALAS) on Oct. 5, 2011 in San Diego, Calif. The poster was entitled “Efficacy Studies of Gel-Delivered Analgesics in Rodent Models of Pain." ClearH2O, a Portland Maine-based company, sponsored the research through a contract to the University of New England. The company also had an exhibition booth at the meeting, displaying their current hydration and nutrition gel products for veterinary and animal care applications. The company has been working with the Bilsky laboratory to develop innovative products that can deliver analgesics for post-operative pain management.
The AALAS meeting is a national meeting held yearly in different locations around the United States and showcases over 200 educational presentations each year. AALAS is a nonprofit membership association and has been able to provide members a premier forum for the exchange of information and expertise in the care and use of laboratory animals since 1950. AALAS is dedicated to the humane care and treatment of laboratory animals and the quality research that leads to scientific gains that benefit people and animals.
Posted on: 10/18/2011
UNECOM Professor Ed Bilsky gives invited lecture at The Scripps Research Institute
Edward Bilsky, Ph.D., UNECOM professor and associate provost for research and scholarship, gave an invited talk at The Scripps Research Institute on Oct. 6, 2011. The presentation, entitled “Animal Models of Pain: Back Translating from Veterinary and Human Clinical Pain States” was presented to the chemistry and biology groups on the La Jolla, California campus.
The talk was part of a series of meetings Dr. Bilsky had with the laboratories of Drs. Dale Boger and Edward Roberts. Several members of the neuroscience group at the University of New England are working with these chemists in trying to develop novel analgesics for acute and chronic pain. Dr. Bilsky also attended the annual American Association for Laboratory Animal Science (AALAS) meeting as part of ongoing efforts to improve animal care in biomedical research. The state of Maine was well represented at the meeting. In addition to UNE, Jackson Laboratories, IDEXX Laboratories and Clear H2O all had presentations or booths at the meeting.
Posted on: 10/18/2011
Maine Dartmouth’s Distinguished Speaker Series features UNECOM Professor Ed Bilsky
Edward Bilsky, Ph.D., associate provost for research and scholarship and UNECOM professor, gave an invited talk at MaineGeneral Health Sept. 28, 2011. The presentation, entitled “UNE’s Center for Excellence in the Neurosciences: A Catalyst for Education, Research and Economic Development,” was presented at the Thayer Campus in Waterville, Maine and streamed to a number of affiliated sites. The talk was part of the Maine Dartmouth Family Medicine Residency Scholarship in Medicine Distinguished Speaker Series. The program features prominent health care providers, scientists and policy makers from Maine and New England.
According to organizer Dr. Greg Feero, “this series explores the stories behind what we do on a daily basis in clinic and is intended to be relaxed and interactive, with the goal of inspiring attendees to question not just the 'how' in their practice, but the 'why' as well as the 'why not.'” Dr. Bilsky provided an overview of the biomedical research initiatives being undertaken at UNE and how the structure of the neuroscience center is contributing to the research and education missions across the university. He described several examples of how CEN faculty and staff are reaching out to local communities to help facilitate health, education and economic development for the state of Maine. More information on MaineGeneral and their speaker series.
Posted on: 10/03/2011
Research by UNE medical student Rob Zondervan is covered by dozens of media outlets
U.S. News & World Report, MSN Health, Health Day, MedPageToday.com, AuntMinnie.com and dozens of other online media outlets ran stories on research presented at the American Roentgen Ray Society annual meeting in Vancouver May 1, 2012, by first-year UNE College of Osteopathic Medicine student Rob Zondervan and colleagues.
The new study of young people who underwent CT scans suggests that their risk of dying from a condition related to their radiation exposure is far less than dying from the original disease they faced. Co-investigators for the study are Susanna Lee M.D., Ph.D., and Peter Hahn M.D. Ph.D., of Massachusetts General Hospital.
Zondervan told AuntMinnie.com (a news outlet for radiologists) that he hopes the study will affect thinking about CT in two ways.
"We now have a list of common CT indications where people interested in radiation reduction can focus their efforts to have maximal impact, and also we now provide mortality rates for these patients showing that, yes, radiation reduction is very important, but also that these patients are at higher risk than the average person, even someone receiving just one scan," he said.
"So it's OK to use CT scanning: These patients are at risk, and the risk of dying from the underlying morbidity is much higher than the risk of dying from radiation-induced cancer," Zondervan said.
"Lowering CT x-ray dose would proportionately decrease the predicted number of radiation- induced cancers, but dose reduction needs to occur in ways that do not result in greater radiologist uncertainty."
Before entering UNE's medical school, Zondervan, was an imaging analysis specialist at the Dana Farber/Harvard Cancer Center: Tumor Imaging Metrics Core in Boston.
Posted on: 05/03/2012
New England Psychologist interviews Marc Hahn for story on COM's commitment to Joining Forces initiative
The New England Psychologist on April 1, 2012 featured a story on the announcement of Joining Forces, an initiative to support the health care needs of service members. The program includes a commitment by 130 U.S. medical schools to increase research and training for brain injuries, PTSD and other mental health issues.
The announcement was made in January at a meeting with First Lady Michelle Obama that Marc B. Hahn, D.O., senior vice president for health affairs and dean of the College of Osteopathic Medicine, attended along with a select group of other medical school deans.
The New England Psychologist story focuses on Hahn and the UNE College of Osteopathic Medicine.
"Marc B. Hahn, D.O., knows how fast the U.S. military can get a soldier injured overseas back on American soil," the story explains. "He was chief of pain management and an attending anesthesiologist on active duty at Walter Reed Army Medical Center during the first Persian Gulf War."
“We were evacuating some injured servicemen so quickly back to stateside that we were dumping out sand from their boots in the operating room,” Hahn recalled in the story.
Joining Forces, Hahn explained, shows a commitment to training the next generation of physicians to be sensitive to post-war injuries and behavioral health issues. The next steps are to focus on training in these areas as part of internships and residencies and ongoing training for physicians who may not have had that exposure during their medical school or graduate medical training.
UNE already has research and curriculum in place to expose students to issues related to PTSD and brain injuries.
The story cites the research that has been conducted at UNE. Edward Bilsky, Ph.D., UNE associate provost for research and scholarship and director of the Center for Excellence in the Neurosciences, explains that this research was performed by medical student Jacque Reynolds in both his laboratory and the laboratory of UNE Professor Ian Meng. The research proposed a novel animal model of Post-Traumatic Stress Disorder that won an award at the 2011 annual meeting of the American Academy of Pain Medicine. The full article has now been published in the journal Life Sciences. Read the entire New England Psychologist story.
Associated Press, the Portland Press Herald, the Boston Globe and other media outlets also covered UNE's involvement in the veterans' initiative in January.
Posted on: 04/02/2012
Keith Egan selected as American Association of Colleges of Osteopathic Medicine Osteopathic Health Policy Fellow
Keith Egan, MS II, has been selected as an American Association of Colleges of Osteopathic Medicine (AACOM) Osteopathic Health Policy (OPHI) Fellow. The OHPI Program enables up to three osteopathic medical students to spend two consecutive months in the government relations department at the AACOM headquarters in order to develop an understanding and operational knowledge of how federal healthcare policy is developed and how to have an effective impact on public policy formulation.
In addition to spending two months in D.C., Keith's responsibilities will include meeting with federal agency policymakers, including, but not limited to, officials at the National Institutes of Health, Centers for Medicare and Medicaid Services, Health Resources and Services Administration, Department of Veterans Affairs, and Department of Education;
attending hearings on Capitol Hill pertaining to health policy and attending meetings of groups such as the Medicare Payment Advisory Commission, Council on Graduate Medical Education, American Osteopathic Association Bureau on Federal Health Programs, as well as conferences and colloquia, as appropriate; developing a thorough understanding of an area of particular health policy interest, as well as health policy in general; and completing a health policy paper.
Keith is the first UNECOM student to be awarded this prestigious fellowship.
Posted on: 5/17/2012
Apryle Seeley receives American Cancer Society Betty Lea Stone Research Fellowship
Apryle Seeley, MSI, has been awarded the American Cancer Society Betty Lea Stone Research Fellowship. This is the first time a UNECOM student has applied for this fellowship, which is specifically for first year medical students in New England. Seeley will receive a $5,000 stipend to conduct laboratory research on prostate cancer for 10 weeks with accomplished investigators such as Massimo Loda, M.D., at the Dana-Farber Cancer Institute, where she will present her research at the end of the summer fellowship (on August 7th).
Posted on: 4/27/2012
Margo Rockwell publishes first article
Margo Rockwell, UNECOM MS III, has become a published researcher. Awarded a UNECOM Dean’s Research Fellowship at the Institute for Aging Research at Hebrew SeniorLife in Boston, Massachusetts, during the summer of 2009, Rockwell’s continued work in geriatrics resulted in the co-authorship and publication of “Height Loss Predicts Subsequent Hip Fracture in Men and Women of the Framingham Study” in the Journal of Bone and Mineral Research, Vol. 27, No. 1, January 2012, pp. 146-152. DOI: 10.1002/jbmr.557.
Rockwell’s onsite mentor during her Research Fellowship was Marian T. Hannan, DSc, MPH, associate professor of medicine and co-director of musculoskeletal research at the Institute for Aging Research, and her UNECOM mentor is Marilyn Gugliucci, Ph.D., Department of Geriatric Medicine. Rockwell’s co-authors of the article are Marian T. Hannan, Kerry E. Broe, Adrienne Cupples, Alyssa B. Dufour, and Douglas P. Kiel.
Posted on: 3/29/2012
Medical students Heather Hassett and Shayna Shackford awarded aging research fellowships
Both medical students will be conducting research at Johns Hopkins Medical School during the 2012 summer months. Hassett will be conducting research in the field of physical medicine and older adult function, while Shackford will be conducting research on dementia and delirium. Marilyn R. Gugliucci, Ph.D., UNECOM director of geriatric education and research, is the UNECOM Research Mentor.
UNECOM has been quite successful in attaining this highly competitive and prestigious AFAR MSTAR Fellowship. To date we have had 18 UNECOM AFAR MSTAR Fellow awardees since 2003.
Posted on: 3/08/2012
Medical student Bryden Considine takes 2nd place award for research poster at SOMA symposium
College of Osteopathic Medicine student Bryden Considine '14 received a 2nd place award for his research poster at the 15th Annual National SOMA Research Symposium in Orlando, Fla. The title of the project was "Role of cathepsin proteases and Niemann-Pick C1 protein in Ebola virus infection." Considine's research was supported this past summer by a COM Dean's Research Fellowship.
The SOMA Research Symposium provides the opportunity for osteopathic medical students to view and present ongoing research. The AOA has long been a supporter of osteopathic medical students becoming involved in research, and AOA and SOMA recognize the role that clinical and basic science research plays in bridging the gap between the laboratory and the bedside. The theme of this year’s research conference was “The Science Supporting the Impact of OMT on the Human Condition: The Structure-Function Relationship and Mechanisms of Action for Self-Regulatory and Healing Processes.”
Posted on: 11/02/2011
Medical Student Jacques Reynolds Has a Research Article Published in Life SciencesMedical Student Jacques Reynolds Has a Research Article Published in Life Sciences
An original research paper from the laboratories of COM faculty members Ian Meng and Edward Bilsky was recently published in the journal Life Sciences. Jacques Reynolds, a 3rd year osteopathic medical student was the first author on this publication. The paper represents the thesis work Mr. Reynolds collected as part of his masters degree from the University of New England. The paper, entitled "Selective ablation of mu-opioid receptor expressing neurons in the rostral ventromedial medulla attenuates stress-induced mechanical hypersensitivity" describes a potential animal model of post-traumatic stress disorder (PTSD). The work also build upon a mechanistic explanation for stress-induced hyperalgesia.
Citation: Reynolds, J., Bilsky, E.J. and Meng, I.D. Selective ablation of mu-opioid receptor expressing neurons in the rostral ventromedial medulla attenuates stress-induced mechanical hypersensitivity. Life Sciences. 89 (2011). 313-319.
Posted on: 9/12/2011