March 14, 2018
Four faculty members from the College of Dental Medicine have been published in the Journal of Community Health, a peer-reviewed publication for health promotion and disease prevention. Assistant clinical professors Adepitan Owosho, B.Ch.D., FAAOM; Rashidah Wiley, D.D.S.; Tessie Stansbury, D.M.D.; and Jon Ryder, D.D.S., M.S., dean of the College of Dental Medicine, studied the trends in human papillomavirus (HPV)-related oropharyngeal cancer incidence in the state of Vermont from 1999 to 2013.
HPV-related oropharyngeal cancers are malignancies that arise from tissues of the throat, including the tonsils, base of tongue, soft palate and the walls of the pharynx. In the study, the team found that the overall incidence of HPV-related oropharyngeal cancer increased significantly during the timespan, specifically in males. They also discovered that there appears to be a decreasing incidence of smoking and alcohol-related oral cavity cancer in Vermont.
Owosho has also been published in the Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology Journal (OOOO).
His study concerned anti-resorptive medication, often used for osteoporosis and cancer treatment, and medication-related osteonecrosis of the jaw (MRONJ), the weakening and loss of the jaw bone. Owosho and his colleagues investigated this relationship in their research, while examining the role of pre-medication dental evaluation (PMDE) in the prevention of MRONJ.
They found that that cancer patients on the drug Denosumab developed MRONJ earlier than those who took Zoledronate and Pamidronate. Pre-medication dental evaluation also significantly reduced the incidence of MRONJ in cancer patients with metastatic bone disease, specifically for those taking anti-resorptive medication to prevent skeletal-related events.
Pre-medication dental evaluation consists of patient education, comprehensive oral and dental evaluation, and the completion of recommended pre-medication dental treatment before taking anti-resorptive medication.
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