Derek Molliver received his B.A. from Williams College in 1988 and went on to complete his PhD in Neuroscience at Washington University in St. Louis in 1997, studying the role of neurotrophic factors in the development of peripheral sensory neuron identity with Dr. William Snider. He then took a postdoctoral fellowship with Dr. Ed McCleskey at the Vollum Institute of Oregon Health and Science University, examining the function of purinergic G protein-coupled receptors (GPCRs) in adult nociceptive sensory neurons. After two years as a Research Associate with Dr. Brian Davis at the University of Pittsburgh, he was appointed in 2004 to Research Assistant Professor of Gastroenterology and in 2006 to Assistant Professor of Gastroenterology and Neurobiology in the newly created Pittsburgh Center for Pain Research. While at the University of Pittsburgh, he managed an NIH-funded research program studying transcriptional and post-translational regulation of nociceptors by neurotrophic factors and purinergic GPCRs. Dr. Molliver joined the University of New England College of Osteopathic Medicine in the Department of Biomedical Sciences as an Associate Professor in the spring of 2014 with an R01 from NIGMS to examine the integration of GPCR signal transduction pathways in inflammatory pain. Current projects focus on the dynamic regulation of intracellular signaling by protein-protein interactions and the use of fluorescence 2-dimensional eletrophoresis, phospho-protein profiling and mass spectrometry to detect changes in the scaffolding of modular signaling complexes.
Washington University in St. Louis
Department of Medicine, University of Pittsburgh
Vollum Institute, Oregon Health and Science University
cell and molecular biology
Neurobiology of acute and pathological pain including neuropathic pain
G protein coupled receptors