March 14, 2018
Karen Houseknecht, Ph.D., professor of Pharmacology in the University of New England College of Osteopathic Medicine and interim dean of the College of Pharmacy, and students Celeste Bouchard (COM, ’20), and Cody Black (COP, ’18), have been published in Mental Health and Clinical Psychology, a journal that publishes research papers dealing with all aspects of depressive, anxiety disorders and Post-Traumatic Stress Disorder (PTSD) for all age groups (child, adolescent, adult and geriatric).
Following her recent publication in the journal, Houseknecht was invited to write a literature review concerning the effect of psychiatric drugs on bone. Houseknecht, Bouchard and Black's manuscript highlights the work of the Houseknecht laboratory and delves into other research that explores the effects of these drugs on bone health.
Bouchard and Black contributed to the review by analyzing published literature on the topic and helping to write specific portions of the manuscript. Bouchard, a Morgane Research Fellow, examined the role of antipsychotic drugs on gene expression in the liver. Black, who plans to pursue a PGY1 residency and an academic fellowship, researched the genetic relationship between mental disorders and predisposition of bone fractures, as well as the key mechanisms of antipsychotic and antidepressant-mediated bone fractures.
“An important mission of our work is to train future healthcare providers in evidence-based medicine,” said Houseknecht. “I wanted to give Celeste and Cody the opportunity to learn more about the clinical side effects of these medications on bone, which are not widely known or understood, and for them to learn what is known about underlying medication-induced bone disease.”
Read the review in the Journal of Mental Health and Clinical Psychology.
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