Associate Dean for Research and Scholarship, College of Osteopathic Medicine
Carol Brenner, PhD, has been doing research in reproductive biology for over 25 years. She has directed NIH-supported extramural and intramural research to investigate chromosomal and mitochondrial anomalies in primate oocytes, embryos, embryonic stem cells and induced pluripotent stem cells. Dr. Brenner worked with Nobel Prize winners such as Professor Robert Edwards, a pioneer in reproductive medicine and in vitro fertilization. Dr. Brenner also worked as the Director of Molecular Embryology, at the Institute for Reproductive Medicine and Science at Saint Barnabas under the direction of Drs. Jacques Cohen, Richard Scott and Santiago Munne, investigating mechanisms of aneuploidy and preimplantation genetic diseases (PGD). She also had the honor to collaborate with Barry Bavister, a well-known reproductive physiologist, who was instrumental with Professor Edwards in discoveries that paved the way for the birth of the first IVF baby in 1978. Dr. Bavister also developed the first reliable procedures for IVF in monkeys.
Dr. Brenner opened an adult stem cell laboratory in collaboration with the Gibbs Cancer Center and the Edward Via College of Osteopathic Medicine-South Carolina (VCOM South Carolina) in March 2013. Dr. Brenner was instrumental starting two new osteopathic schools,VCOM South Carolina and New York Institute of Technology, College of Osteopathic Medicine at Arkansas State (NYITCOM @ A-State). Her research projects at NYITCOM @ A-State improving the quality of health care in rural, underserved communities of northeast Arkansas. Dr. Brenner is now the Associate Dean for Scholarship and Research at the University of New England College Osteopathic Medicine.
(San Francisco, California)
· Brenner CA, Adler RR, Rappolee DA, Pedersen RA and Werb Z (1988). Gene expression of metalloproteinases and their inhibitors in preimplantation mouse embryos. Genes Dev. 4:348-359.
· Rappolee DA, Brenner CA, Schultz R, Mark D and Werb Z (1988). Developmental expression of PDGF, TGF-alpha and TGF-beta genes in preimplantation mouse embryos. Science. 241:1823-1825.
· Lonergan T, Bavister B, Brenner C (2007) Mitochondria in stem cells. Mitochondrion. 7|:289-296.
· Parker GC, Acsadi G, Brenner CA (2009) Mitochondria|determinants of stem cell fate? Stem Cells Dev. 18:803-806.
· Harvey A, Gibson T, Lonergan T and Brenner CA (2011) Dynamic Regulation of Mitochondrial Function in Preimplantation Embryos and Embryonic Stem Cells. Mitochondrion, 11:829-838.
Areas of Research expertise: Infertility IVF, preimplantation genetics, embryology, and stem cell biology. NIH Grant funded Research Projects: Mitochondrial function in embryonic and induced pluripotent stem cells.