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Lauren Payne

Lauren is a homegrown Mainer with an abundance of state pride. After graduating from John Bapst Memorial High School in Bangor, she began her undergraduate studies at the University of Maine before transferring to the University of New England (UNE) to complete her Doctor of Pharmacy degree. Lauren then completed two years of postgraduate residency training at Maine Medical Center (MMC) in Portland, earning a specialty in critical care pharmacy. Her numerous teaching opportunities, including completion of a teaching certification program, fostered a real passion for academia, and Lauren is now continuing her career as a clinical professor with a practice site at MMC -- training future pharmacists and taking care of trauma patients. Lauren’s job is fast-paced, demanding, and never dull. She absolutely loves it!

Clinical Affiliations

Clinic Name

Maine Medical Center




Research Interests

Pain, Agitation, Delirium, and Sleep in the Intensive Care Unit

Phenobarbital for Alcohol Withdrawal 

Phenobarbital for Refractory Agitation 

Melatonin for Prevention of Delirium 

Multimodal Approaches to Pain Management, including intravenous lidocaine, gabapentin, and pregabalin. 

Selected Publications


Payne LE, Gagnon DJ, Riker RR, et al. Cefepime-induced neurotoxicity: a systematic review. Crit Care. 2017;21(1):276.

Other Scholarly Activity


Power Pak C.E. “A Review of Pharmacotherapy Management of Pain, Agitation, and Delirium in Adult Patients in the ICU" 2016




Contributor, Clinical Practice Guideline for the Management of Pain, Agitation, Delirium, Early Mobility, and Sleep in Adult ICU Patients; the American College of Critical Care Medicine


Research Topics

Lauren Payne

Lauren Payne



Assistant Clinical Professor

Portland Campus

Pharmacy Building

(207) 221-4178

On Campus