Stephen Fox hails from the United Kingdom. He moved to the United States in Fall 1981. As a graduate student he developed interest and skill in the synthesis of transition-metal complexes with chelating ligands. As a post-doctoral scholar at The Johns Hopkins University he studied complexes that modeled the structure of cytochrome oxidase. As a faculty member at the University of Louisiana-Monroe he initiated a research program involving a novel chelating ligand — naphthyridinediimine, to prepare complexes of two metals in mutual close proximity. He arrived at UNE in Fall 2010; it is his honor to be here as both a science educator and a scientist — a teacher-scholar!
SUNY at Stony Brook
University of Georgia
B. Sc. (Hons)
University of St. Andrews
Johns Hopkins University
Bioinorganic Chemistry; synthesis of novel organic ligands; model compounds of metalloprotein active sites; coordination chemistry
As his primary research interest, Dr. Fox synthesizes and studies multi-metallic complexes of novel naphthyridine ligands. In this context, he has prepared a class of dicopper(I) compounds with unusually short separations between the metal centers similar to what is found in the enzyme site known as "Copper A;" he is currently studying the reactivity of these compounds. A secondary interest concerns the synthesis and study of novel platinum(II) complexes and the study of their interactions with DNA.
Bioinorganic chemistry; diimine modified 1
Fox, S.; Fronczek, F. R.; Valente, E. J. "Halide-bridged dicopper(I) naphthyridine-diimine "crescent" complexes bearing short metal-metal distances" Abstracts of Papers, 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008, INOR-159
Holzer, S.; Fronczek, F. R; Young, Jr., V. G.; Fox, S. “Synthetic and structural studies of the trans-bis(2-N-H-pyrrolylcarbaldimine) complexes of nickel(II) and palladium(II)” J. Chem. Crystallogr. 2006, 36, 883-889.
Fielding, A. J.; Fox, S.; Millhauser, G. L.; Chattopadhyay, M.; Kroneck, P. M. H.; Fritz, G.; Eaton, G. R.; Eaton, S. S. “Electron Spin Relaxation of Copper(II) Complexes in Glassy Solution between 10 and 120 K” J. Magn. Res. 2006, 179(1), 92-104.
Chen, Q.; Buss, C. E.; Young, Jr., V. G.; Fox, S. “Synthesis and structural studies of tris-2-chlorobenzylamine and tris-2-bromobenzylamine” J. Chem. Crystallogr. 2005, 35, 177-181.
Simpson, J. L.; Lombardo, D. J.; Fox, S. “Spectroscopic and Structural Studies of a Palladium(II) Pyrrolate-imine Complex” J. Und. Chem. Res., 2004, 3(2), 71-77.
Wansapura, C.; Juyoung, C.; Simpson, J. L.; Szymanski, D.; Eaton, G. R.; Eaton, S. S.; Fox, S. “From Planar Toward Tetrahedral Copper(II) Complexes: Structural and Electron Paramagnetic Resonance Studies of Steric Effects Imparted by a Class of Pyrrolate-imine Ligands” J. Coord. Chem 2003, 56, 975-993.
Vu, C.; Walker, D.; Wells, J.; Fox, S. “Elaboration of 1,8-Naphthyridine-2,7-Dicarboxaldehyde into Novel 2,7 Dimethylimine Derivatives” J. Heterocyclic Chem 2002, 39, 829-832.