Steven (Steev) C Sutton

Dr. Steven 'Steev' C. Sutton received his B.S. Pharmacy Cum Laude from Massachusetts College of Pharmacy, Boston, and his Ph.D. in Pharmaceutical Sciences from the State University of New York at Buffalo. Dr. Sutton, a Rho Chi member, worked as a retail pharmacist in Harvard Square and Lowell, MA before returning to school. After graduate school he joined the General Pharmaceutics Group, Ciba-Geigy (now Novartis), for several years. Dr. Sutton and his family then moved to Lawrence, KS where he worked at INTERx Research Corporation, (founded by Takeru Higuchi, the 'father of physical pharmacy', and a subsidary of  Merck & Co). 

Dr. Sutton then moved back to New England and joined Pfizer Labs in Groton, CT in what was then called the Pharmaceutical R&D Department. In 2009, he embarked on his second career of teaching as an inaugural faculty at the College of Pharmacy at the University of New England, Portland, Maine.

Dr. Sutton has been active in his professional organization the American Association of Pharmaceutical Scientists (AAPS). For example, he founded the AAPS Oral Absorption Focus Group, and was a founding member of both the Hudson Valley and Kansas City Pharmaceutics Discussion Groups. He served as General Chair of the AAPS Midwest Regional Meeting, as well as organized numerous national meeting symposia over the years. He is also a member of the editorial board of the AAPS PharmSciTech and The AAPS Journal. Dr. Sutton is a research Fellow of the American Association of Pharmaceutical Scientists, and a Fellow of the American Academy of Veterinary Pharmacology and Therapeutics. Dr. Sutton has had a visiting scientist status at MCPHS, College of Pharmacy, and SUNY at Buffalo, College of Pharmacy. Previously, he also held adjunct professor appointments at the School of Pharmaceutical Sciences, Kansas University (KU), Lawrence, the School of Pharmacy, University of Missouri-Kansas City (UMKC) and at the University of Connecticut, School of Pharmacy. At KU and UMKC, he served as a member on Ph.D. research committees. 

Dr. Sutton has authored or co-authored about 130 book chapters, abstracts of work in progress, invited presentations and patents. 

Dr. Sutton met his wife, Kimberly in graduate school. They have three children: Brenton (an employee of Origene, Inc., Rockville, MD), Alexander (an Analyst at BCG, Boston) and Katherine (a food scientistsat Purina in Australia).

Dr Sutton's personal interests include hiking, fine woodworking and trying to grow tomatos.



State University of New York at Buffalo


Massachusetts College of Pharmacy

Board Certifications and Licenses

Pharmacy: MA, NY



Physical Pharmacy

Cell Culture


Current Research

A Farnham, SH Stafford, SC Sutton: Impact of Dose on Amount of Polystyrene Nanoparticles Translocated Across Caco-2 Cell Monolayers, AAPS NERDG Annual Meeting, Farmington, CT, April 20, 2017.

A Farnham, SC Sutton: An HT29 Cell Monolayer Model to Investigate the Cumulative Genotoxic Effects of POPs and Nanoparticles, AAPS NERDG Annual Meeting, Farmington, CT. April 19, 2016.

Duong, S. and S. C. Sutton: Predicting the Physiologically Relevant Precipitation Rate of Weakly Basic Drugs Using Potentiometric Titration. AAPS National Meeting, San Antonio, TX, AAPS, 2013.


Research Interests

Determine the impact of chronic low-level orally ingested persistent organic pollutants (POPs) and nano particles on the immune system via the intestines.

Selected Publications


Sutton, S. C., R. Nause and K. Gandelman (2017). "The impact of gastric pH, volume, and emptying on the food effect of ziprasidone oral absorption." The AAPS Journal: 1-7 (published online 20 March 2017

Thombre, A.G., W.B. Caldwell, D.T. Friesen, S.B. McCray, and S.C. Sutton, Solid Nanocrystalline Dispersions of Ziprasidone with Enhanced Bioavailability in the Fasted State. Molecular Pharmaceutics, 2012, 9:3526-3534

Claxton, R., Endrenyi, L., Lucas, A., Martinez, M. & Sutton, S.  Estimating product bioequivalence for highly variable veterinary drugs. J Vet Pharmacol Therap, 2012, 35:11-16.

Steven C. Sutton, The Use of Gastrointestinal Intubation Studies For Controlled Release Development. British Journal of Clinical Pharmacology, 2009. 68(3): p. 342-354.

Sutton, S.C., Role of Physiological Intestinal Water in Oral Absorption. The AAPS Journal, 2009. 11(2): p. 277-285

Other Scholarly Activity

Sutton, S. C. (2017). Chapter 3. Drug Administration and Drug Absorption. Basic Pharmacokinetics and Pharmacodynamics. S. Rosenbaum. Hoboken, NJ, Wiley: 35-70.

Sutton, S. C. (2017). Chapter 9. Pharmacokinetics of Extravascular Drug Administration. Basic Pharmacokinetics and Pharmacodynamics. S. Rosenbaum. Hoboken, NJ, Wiley: 201-224

Sutton, S.C (2013) Chapter 6: “Biopharmaceutics and veterinary drug delivery”, In: Animal Health Drug Delivery, Michael Rathbone (Ed), Controlled Release Society, The Springer Publishing Company, New York 

Sutton, S.C (2013) Chapter 4: “Anatomy and physiology of the companion animal”, In: Animal Health Drug Delivery, Michael Rathbone (Ed), Controlled Release Society, The Springer Publishing Company, New York 

Jaymin Shah, Steve Sutton, Susan Way, Gayle Brazeau (2013) “Parenteral Formulations: Local Injection Site Reaction and Muscle Tolerance”, In: Encyclopedia of Pharmaceutical Technology Third Edition, James Swarbrick (ed) Informa Healthcare USA, Inc., New York 

Sutton, S.C., P. Smith (2011) Chapter 3. Animals Suitable for Modeling Controlled Release, In: “Oral Controlled Release”, Clive Wilson, Brigitte Skalsky & Patrick Crowley (eds), Controlled Release Society, The Springer Publishing Company, New York.


Funded Grants


UNE Minigrant: “Physical-chemical characterization of fluorescent polystyrene nanoparticles after incubation in cell culture and digestive media”. Jun 2017-May 2018 ($3,846). 

Maine INBRE RRC grant: Analysis of polycyclic-aromatic hydrocarbons by GCMS. 2015-16 ($1490.00).

UNE Minigrant: “Studies to determine the oral bioavailability of POPs from microplastic in mussels” Co-Investigator: Stephan Zeeman. Jun 2013-May 2014 ($7,800).     

FDA: Development of FDA Reviewer Training Module "Biophysical Foundation of Pharmacokinetics and Biopharmaceutics" (NIPTE (PI), Rosemont, IL). 2013-2014 ($40,000).

Invited Plenary Presentation

Sutton, SC. Challenges When Working with Different Animal Species. USP Workshop on In vitro Testing for Meeting Future Challenges for Veterinary Dosage Forms, March 14–15, 2016 ž USP Meetings Center, Rockville, Maryland.

Sutton, SC. Interspecies intestinal differences and impact on oral dosage forms for animal health” to be presented at the joint CRS/AAPS workshop “Animal Health Drug R&D: Formulation, Delivery and Development to Market”, November 1-2, 2014, in San Diego

Sutton, SC. The anatomy & physiology of interspecies’ biopharmaceutics, presented at the “Interspecies clinical pharmacology dosing concepts” mini-symposia, at the 2014 Annual Meeting of the Controlled Release Society, July 13-16, 2014, in Chicago

Sutton, SC. Predictive Animal Models for Assessing Long-Acting Formulations for Human and Animal Health, presented at the Inaugural Controlled and Modified Drug Release Conference in Philadelphia, PA on May 7-8, 201

Sutton, SC. Critical Features of Solubility and Permeability that can Limit the Food Effect, presented at the 2nd annual Drug Formulation & Bioavailability – West Coast, in San Diego, CA, on June 2-3, 2014

Sutton, S. C.: Biopharmaceutics and Pharmacokinetics of the Food Effect, presented at the Roundtable: When Food Impacts Oral Drug Exposure: The Nature and Study of the Food Effect. AAPS National Meeting, San Antonio, Nov., 2013.

Sutton SC. Utilizing in silico, in vitro and preclinical methods to optimize your clinical prediction from biopharmaceutic modeling. ExlPharma’s 2nd Enhancing Drug Bioavailability and Solubility Conference, Boston, MA January, 2013

Research Topics

Photo of Steev

Steven (Steev) C Sutton


BS Pharmacy, PhD Pharmaceutical Sciences

Associate Professor of Pharmaceutical Sciences; A.A.P.S. Fellow, A.A.V.P.T. Fellow;

Portland Campus

Pharmacy Building

(207) 221-4173

On Campus

Eligible for Student Opportunities