James Vesenka

History and Research:

The moniker "Dr. V" is in veneration to his late father, an outstanding teacher in the Concord Massachusetts school system who went by the name of "Mr. V."  Dr. V teaches general physics and undertakes research in molecular self-assembly of four-stranded DNA and physics education.  He graduated Magna Cum Laude and Phi Beta Kappa from Clark University with a dual major in chemistry and physics in 1982.  He graduated with a M.Sc. and Ph.D in physics, with an emphasis in biological physics, from the University of California, Davis in 1989.  Dr. V's post-doctoral training included research at the Institute for Molecular Biology and Signal Transduction Training Group at Iowa State University.  He published nearly 50 articles and received patents for developing the scanning probe microscope (SPM) for use in high resolution imaging of biomolecules and developing techniques to reconstruct true surface topography due to probe artifacts.  Dr. V was an assistant professor in the Department of Physics at California State University Fresno (CSUF) in 1995, continuing is four-stranded DNA research and establishing a California State University-wide scanning probe microscopy facility.  He began teaching general physics and continuing both lines of research at the University of New England in 2000.  Dr. V has received funding from the Research Corporation and National Science Foundation to set up scanning probe microscopy facilities at CSUF and UNE.  His recent undergraduate research examined the auto-orientation of the self-assembled four-stranded DNA on the surface of phyllosilicates[i].  Recently, he initiated a new collaboration with Bigelow Ocean Labs to undertake near-field characterization of iron-oxidizing bacteria. All of Dr. V's 17 graduated research assistants have gone on to professional schools, primarily to study medicine.  He also has used the SPM in conjunction with the modern physics component of the introductory physics lab to image atoms in real time as models for quantum mechanics in action. 

Physics Modeling Instruction:

Dr. V's teaching style is strongly influence by research-based "modeling instruction".  This approach to physics learning is based on guided inquiry and Socratic questioning, compelling students to confront physics misconceptions and construct knowledge based on the scientific method.  A four-year study involving the results from research-based assessments involving CSUF and UNE students clearly established the efficacy of modeling instruction over traditional physics education[ii].  Dr. V continues his physics education research, successfully persuading the UNE administration to switch from the traditional lecture/lab format to "studio physics" in which both lecture and lab are taught in the  more intimate setting of a laboratory classroom.  The instruction has been highly influenced by the latest developments in Physics Education Research (PER) including adoption of many lab activities on fluids that were outcomes from Dr. V's NSF funded research in PER.  In particular the studio physics instruction at UNE is undergoing a change to include more Introductory Physics for the Life Sciences since over 95% of UNE physics students major in either health of life sciences.  The content is geared more towards authentic biological applications of physics, a growing part of PER research at UNE.



Clark University



University of California, Davis


Post-Doctoral Training

Signal Transduction Training Group

Iowa State University



Post-Doctoral Training

Institute of Molecular Biology

University of Oregon




Physics education pedagogy

physical science teacher training

scanning probe microscopy.

biomaterials nanotechnology


Current Research

Development of biologically rich general physics curriculum consistent with modeling physics instruction. Characterization of structural, electrical and magnetic properties of the iron oxidizing bacteria leptothrix ochracea through scanning probe microscopy.

Research Interests

Modeling instruction training of K-12 physical science teachers. College-level general physics curriculum development in fluids. Scanning probe microscopy of self-assembled four stranded "G-quartet" DNA and iron oxidizing bacteria.

Selected Publications


Sarah Yerkes, James Vesenka, and Eric B. Kmiec. A stable G-quartet binds to a huntingtin protein fragment containing expanded polyglutamine tracks. Journal of Neuroscience Research 88, 335-345 (2009).





M. Weglarz, W. Fritzsche, S. Yerkes, E. Kmiec, & J. Vesenka, ÒAnalysis of G5x Quadruplex DNAÓ, DNA-Based Nano-Scale Integration, AIP Conference Proceedings 1062, pp. 123-128 (2008).


J. Vesenka, D. Bagg*, A. Wolff, A. Reichert, & W. Fritzsche, ÒAuto-Orientation of G-wire DNA on MicaÓ, Colloids and Surfaces B: Biointerfaces, 58, pp. 256-263 (2007).


E. K. Whitmore, D. Grimm, B. Moser, R. Lindell, and J. Vesenka " A kinesthetic circulatory system model for teaching fluid dynamics " under review in Physics Education Research Conference 2015 Proceedings, AIP Press.

Funded Grants

NSF Transforming Undergraduate Research in STEM Award DUE-1044154

Research Topics

James V

James Vesenka



Professor, Physics

Director of Microscopy Core Facility

Biddeford Campus

Morgane Hall


(207) 602-2560

On Campus