Matrix Revolutions: Perlecan Domain V as a Novel Stroke Therapy
Dr. Bix's current research interests is in the role of the extracellular matrix in stroke (third leading cause of mortality in the United States). Vascular matrix components are often very sensitive to proteolytic processing/degradation in models of focal cerebral ischemia. Often such processing will generate biologically active matrix fragments. One focus of his laboratory is to determine how select matrix fragments affect the neurovascular unit, the functional multicellular unit that is perturbed in stroke. Another focus of his laboratory is to determine what role these matrix fragments could play in neurodevelopment involving processes that are often recapitulated in response to CNS injury.
Lunch will be provided.
Hosted by: Colin Willis, Ph.D.
Alfond Room 304