Prior to joining the University of New England, I worked for 18 years in the pharmaceutical industry. During that time, I became an expert in bioanalytical chemistry and the development, validation, and execution of methods to detect drugs, typically small molecules, in blood, plasma, urine, milk, and other matrices. Initially, my work used primarily liquid chromatography with ultraviolet detection. As demand for more sensitive methodology increased, I moved into the area of triple quadrupole mass spectrometry, employing this technique for a variety of drug metabolism, pharmacokinetic, and physical chemical property determinations.
As a research technician at UNE, my role is to develop and validate bioanalytical methods for the detection and quantitation of various analytes of interest in a variety of matrices. Principal methodology includes protein precipitation, liquid/liquid extraction, solid phase extraction, with detection by reversed phase liquid chromatography-triple quadrupole mass spectrometry.