Douglas B. Spicer, Ph.D., M.MEdL
Associate Professor, Biomedical Sciences
Harvard Medical School (, )
Spicer DB, Thompson KH, Kilgallen S. Making the connection: Using concept mapping to bring the basic sciences to the diagnosis. JAOA. 2020;120(8): 524-528
Spicer DB, Thompson KH, Tong MS, Cowan TM, Fulton TB, Lindsley JE. Medical biochemistry without rote memorization: multi-institution implementation and student preceptions of a nationally standardized metabolic map for learning and assessment. Med. Sci. Edu. 2018. https://rdcu.be/91wm
Spicer DB, Rowe R, Kilgallen S, Thompson KH. Concept mapping as a tool to promote cognitive integration. IAMSE Annual Meeting, Burlington, VT, June 2017
Thompson KH, Spicer DB, Kilgallen S, Rowe R, Winterson BH. Student perceptions of integrated vs basic science and clinical resources. Association of Biochemistry Educators Biannual Meeting, Clearwater Beach, FL, May 2017
Guzzo RM, Alaee F, Paglia D, Gibson JD, Spicer DB, and Drissi H. Aberrant expression of Twist1 in diseased articular cartilage and a potential role in the modulation of osteoarthritis severity. Genes & Diseases. 2016; 3(1);88-99.
Rowe RJ, Thompson KH, Spicer DB. Identification of “at risk” students in Osteopathic Medical Knowledge I. IAMSE Annual Meeting, Leiden, Netherlands, June 2016
Jacqueroud L, Bouard C, Richard G, Devouassoux-Shisheboran M, Terreux R, Pierrot A, Spicer DB, Caramel J, Payen L, Puisieux, Tissier A, Ansieau S. The heterodimeric TWIST1/E12 complex drives the oncogenic potential of TWIST1 in human mammary epithelial cells. Neoplasia. 2016 May;18(5):317-27.
Spicer DB, Van Deusen J, Thompson KH. Small group facilitation effects on student learning. IAMSE Annual Meeting, San Diego, CA, June 2015
Spicer DB, Van Deusen J, Thompson KH. Identification of facilitation skills that promote student learning. University of New England Board of Trustees Meeting, November 2014
Spicer DB, Thompson KH, Winterson BJ. Development of a flexible learning space for use in an integrative team-based curriculum. IAMSE Annual Meeting, Nashville, TN, June 2014
Spicer DB, Thompson KH, Winterson BJ. Development of a flexible learning space for use in an integrative team-based curriculum. AACOM Annual Meeting, Washington DC, April 2014
Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB. Twist1 controls a cell-specification switch governing cell fate decisions within the cardiac neural crest. PLoS Genet. 2013;9(3):e1003405
Spicer DB, Kilgallen S, Binks A, LeClair R, Winterson BJ, Thompson KH. Concept Map Assessment as a Tool for 2nd Year Medical Student Review and Feedback for 1st Year Students. IAMSE Annual Meeting, St Andrews, Scotland. June 2013
Thompson KH, Binks A, Cao L, Dane P, Kilgallen S, LeClair R, Spicer DB, Van Deusen J, Winterson BJ. Concept Maps Support Integration of Content across Biomedical Sciences and Clinical Case Scenarios. IAMSE Annual Meeting, St Andrews, Scotland. June 2013
Morel AP, Hinkal GW, Thomas C, Fauvet F, Courtois-Cox S, Wierinckx A, Devouassoux-Shisheboran M, Treilleux I, Tissier A, Gras B, Pourchet J, Puisieux I, Browne GJ, Spicer DB, Lachuer J, Ansieau S, Puisieux A. EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice. PLoS Genet. 2012; 8(5):e1002723.
Connerney J, Spicer DB. Signal transduction pathways and their impairment in syndromic craniosynostosis, in Monographs in Human Genetics. Craniosynostoses: Molecular Genetics, Principles of Diagnosis and Treatment, M. Muenke, H. Collmann, W. Kress, and B.D. Solomon, Editors, Karger. 2011; 28-44.
Guzzo R, Andreeva V, Spicer DB*, and Drissi H*. Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice. J Int Dev Biol. 2011; 55:641-7. *equal contribution.
Chakraborty S, Wirrig EE, Hinton RB, Merrill WH, Spicer DB, Yutzey KE. Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves. Dev Biol. 2010; 34(1)7:167-79.
Spicer, D. FGF9 on the move. Nat. Genet. 2009; 41:272-273.
Connerney, J., V. Andreeva, Y. Leshem, M.A. Mercado, K. Dowell, X. Yang, V. Lindner, R.E. Friesel, and D.B. Spicer. Twist1 homodimers enhance FGF responsiveness of the cranial sutures and promote suture closure. Dev. Biol. 2008; 318; 323-334.
Connerney, J., Y. Leshem, V. Andreeva, C. Muentener, M. Mercado, and D.B. Spicer. Twist dimer selection regulates cranial suture patterning and fusion. Dev. Dyn. 2006; 235: 1345-1357.
Clinical reasoning skill development
Active learning pedagogies in medical education
Innovations in medical education
Online education for health sciences