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Glenn W. Stevenson

Before joining the faculty in 2005, Dr. Stevenson had two successful careers: one as a professional musician in Boston; the other working for luxury hotel brands in Washington, D.C. and Boston. Dr. Stevenson embarked on his third career by completing a Ph.D. in Behavioral Neuroscience at American University and trained in the Psychopharmacology laboratory of Dr. Anthony L. Riley. Following his graduate training, he did a post-doctoral fellowship in Pharmacology in the laboratory of Dr. Steve Negus at McLean Hopspital / Harvard Medical School.

Education

Ph.D.

American University

2002

M.A.

American University

1992

B.A.

Muhlenberg College

1986

Post-Doctoral Training

Pharmacology

McLean Hospital-Harvard Medical School

2002 - 2005

Expertise

Drug development; preclinical methods development; opioid pharmacology; pain; exercise; drug abuse; drug interactions

Research

Research Interests

- Medications development & evaluation for the treatment of chronic pain and drug abuse
- Opioid receptor interactions
- Gut microbiome regulation of peripheral and central inflammation and pain

Selected Publications

(*Signifies current or former UNE CAS undergraduate, COM, or CDM student co-author)

Stevenson GW, Giuvelis D, *Cormier J, *Cone K, *Atherton P, *Krivitsky R, *Warner E, *St. Laurent B, *Dutra J, Bidlack JM, Szabò L, Polt R, Bilsky EJ. Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration. Psychopharmacology, in press, 2020.

*Cone K, *Lanpher J, *Kinens A, *Richard P, *Couture S, *Brackin R, *Payne E, *Harrington K, Rice KC, Stevenson GW. Delta/mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression: assessment of therapeutic index in male Sprague Dawley rats. Psychopharmacology, 235(5):1609-1618; 2018.

*Cormier J, *Cone K, *Lanpher J, *Kinens A, Henderson T, Liaw L, Bilsky EJ, King T, Rosen CJ, Stevenson GW. Exercise reverses pain-related weight asymmetry and differentially modulates trabecular bone microarchitecture in a rat model of osteoarthritis. Life Sciences, 180:51-19; 2017.

*Warner E, *Krivitsky R, *Cone K, *Atherton P, *Pitre T, *Lanpher J, Giuvelis D, Bergquist I, King T, Bilsky EJ, Stevenson GW. Evaluation of a post-operative pain-like state on motivated behavior in rats: Effects of plantar incision on progressive-ratio food-maintained responding. Drug Development Research, 76(8):432-441; 2015.

Stevenson GW, *Luginbuhl A, *Dunbar C, *LaVigne J, *Dutra J, *Atherton P, *Bell B, *Cone K, Giuvelis D, Polt R, Streicher JM, Bilsky EJ. The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. Pharmacology, Biochemistry and Behavior, 132:49-55; 2015.

Stevenson GW, *Mercer H, *Cormier J, *Dunbar C, *Benoit L, *Adams C, *Jezierski J, *Luginbuhl A, Bilsky EJ. Monosodium iodoacetate-induced osteoarthritis pain-depressed wheel running in rats: Implications for preclinical behavioral assessment of chronic pain. Pharmacology, Biochemistry and Behavior, 98:35-42; 2011.

Stevenson GW, Bilsky EJ, Negus SS. Targeting pain-suppressed behaviors in preclinical assays of pain and analgesia: Effects of morphine on acetic acid-suppressed feeding in C57BL/6J mice. The Journal of Pain, 7(6):408-416; 2006.

Stevenson GW, Folk JE, Rice KC, Negus SS. Interactions between delta and mu opioid agonists in assays of schedule-controlled responding, thermal nociception, drug self-administration, and drug versus food choice in rhesus monkeys: Studies with SNC80 and heroin. The Journal of Pharmacology and Experimental Therapeutics, 314:221-231; 2005.

Funded Grants

NIH (NIGMS) P20GM103643 (Grant PI: Ian Meng): Pilot project Title: Effects of gut microbiome modulation on neuroimmune function and pain-related behaviors in rheumatoid and osteoarthritis. Funding Period: Sept, 2017-Aug 2020. Funding Institute: National Institute of General Medical Sciences. Role: Pilot project PI

NIH (NIAMS) 2R15 AR054975-02A1: Project Title: Characterization of delta/mu opioid receptor interactions on chronic osteoarthritis pain-depressed behaviors and bone / joint pathology. Funding Period: June, 2014-May, 2017. Funding Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases. Role: Principal Investigator

NIH (NIDA) SBIR 2R44DA26653-02: Sub-project Title: Characterization of the reinforcing effects of mixed-action delta/mu opioid receptor compounds using the drug self-administration procedure in rats. Funding Period: April, 2012-March 2013. Funding Institute: National Institute on Drug Abuse. Role: Sub-project PI

NIH (NIAMS) R15 AR054975-01 : Project Title: Measurement of pain-suppressed behaviors in rodent models of chronic pain. Funding Period: June, 2007-May 2010. Funding Institute: National Institute of Arthritis and Musculoskeletal and Skin Diseases. Role: PrincipaI Investigator

Glenn Stevenson

Glenn W. Stevenson

,

Ph.D.

Professor of Psychology

Program Coordinator, Neuroscience

Decary Hall
329

gstevenson@une.edu

(207) 602-2285

On Campus