Associate Professor of Medicinal Chemistry,
Department of Pharmaceutical Sciences and Administration
Ron Hills is a tenured faculty at the University of New England campus in Portland, Maine. Since joining the School of Pharmacy in 2010, he has taught courses in biochemistry, medicinal chemistry, computer programming, and pharmacology. Dr. Hills' research specialty is in multiscale computational modeling. His interests also include the role of lipids and nutrition in chronic health and disease, which he incorporates in his teaching.
Students working in Dr. Hills' laboratory use computer modeling methods to simulate the molecular dynamics of membrane protein systems relevant to drugs and disease. Topics of focus include the role of lipid-protein interactions in cell function and acquired multidrug resistance associated with ABC transporters.
Protein structure and function
University of Utah, 2008-2010
White, A.M.B., H.R. Mishcon, J.L. Redwanski and R.D. Hills Jr. 2020. Statin treatment in specific patient groups: Role for improved cardiovascular risk markers. Journal of Clinical Medicine 9:3748. Article
Hills Jr., R.D., B.A. Pontefract, H.R. Mishcon, C.A. Black, S.C. Sutton and C.R. Theberge. 2019. Gut microbiome: Profound implications for diet and disease. Nutrients 11:1613. 2020 Editor's Choice, Article
Hills Jr., R.D. 2018. Refining amino acid hydrophobicity for dynamics simulation of membrane proteins. PeerJ 6:e4230. Article
Fosso-Tande, J., C. Black, S.G. Aller, L. Lu and R.D. Hills Jr. 2017. Simulation of lipid-protein interactions with the CgProt force field. AIMS Molecular Science 4:352-69. Article
Hills Jr., R.D. and N. McGlinchey. 2016. Model parameters for simulation of physiological lipids. Journal of Computational Chemistry 37:1112-18. Article
Multiscale modeling and biomolecular simulation
Lipids and cell membrane dynamics
Multidrug resistance transport proteins