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Ron Hills

Ron Hills is a tenured faculty in the Department of Pharmaceutical Sciences at the University of New England in Portland, Maine. Since joining the College of Pharmacy in 2010, he has taught courses in biochemistry, medicinal chemistry, computer programming, and pharmacology. Dr. Hills' research specialty is in computer modeling. His interests also include the role of nutrition in health and disease, which he incorporates in his teaching.

Students working in Dr. Hills' laboratory use computer simulation methods to study the molecular biophysics of membrane protein systems relevant to drugs and disease. Topics of focus include the role of lipid-protein interactions in cell function and acquired multidrug resistance associated with ABC transport proteins.


Ph.D., Biophysics

Scripps Research Institute


B.S., Summa Cum Laude, Biochemistry

Florida State University


Post-Doctoral Training

NIH Kirschstein Postdoctoral Research Fellow, 2009-2010

University of Utah and University of Chicago



Medicinal chemistry



Research Interests

  • Multiscale modeling and biomolecular simulation
  • Lipids and cell membrane dynamics
  • Multidrug resistance transport proteins

Selected Publications

Hills Jr., R.D., B.A. Pontefract, H.R. Mishcon, C.A. Black, S.C. Sutton and C.R. Theberge. 2019. Gut microbiome: Profound implications for diet and disease. Nutrients 11:1613.  Article

Hills Jr., R.D. and E. Erpenbeck. 2018. Guide to popular diets, food choices, and their health outcome. Health Care Current Reviews 6:223.  Article

Hills Jr., R.D. 2018. Refining amino acid hydrophobicity for dynamics simulation of membrane proteins. PeerJ 6:e4230.  Article

Fosso-Tande, J., C. Black, S.G. Aller, L. Lu and R.D. Hills Jr. 2017. Simulation of lipid-protein interactions with the CgProt force field. AIMS Mol. Sci. 4:352-69.  Article

Hills Jr., R.D. and N. McGlinchey. 2016. Model parameters for simulation of physiological lipids. J. Comput. Chem. 37:1112-18. Featured on inside journal cover.  Article

Funded Grants

NSF MCB-1516826      Hills (PI)     9/1/15 – 8/31/19.     RUI: Multiscale models for ABC transporter molecular dynamics.    Goal: Dissect lipid-protein molecular interactions and mutual adaptation in multidrug exporters.    Role: Principal Investigator.    Total Cost: $374,885    Summary

Ronald Hills

Ron Hills



Associate Professor

Graduate Program Coordinator

College of Pharmacy

Portland Campus

Pharmacy Building

(207) 221-4049

On Campus

Eligible for Student Opportunities