CEN Publications


Goode DJ, Whitaker EE, Mecum NE. Ovariectomy increases paclitaxel-induced mechanical hypersensitivity and reduces anti-inflammatory CD4+ T cells in the dorsal root ganglion of female mice. J Neuroimmunol. 2022;367:577878.

Sullivan C, Lee J, Bushey W, Demers D, Dinsdale S, Lowe K, Olmeda J, Meng ID. Evidence for a phenotypic switch in corneal afferents after lacrimal gland excision. Exp Eye Res. 2022 Feb; May ;218:109005.

Townsend K, Imbert I, Eaton V, Stevenson GW, King T. Voluntary exercise blocks ongoing pain and diminishes bone remodeling while sparing protective mechanical pain in a rat model of advanced osteoarthritis pain. Pain.2022 Mar 1;163(3):e476-e487.

Karamchedu NP, Fleming BC, Proffen BL, Sant NJ, Portilla G, Parola LR, Molino J, Murray MM. Terminal sterilization influences the efficacy of an extracellular matrix-blood composite for treating posttraumatic osteoarthritis in the rat model. J Orthop Res. 2022 Mar;40(3):573-583.

Green E, Barlow D, Rostama B, Berkner P, May M. Predictive Values of Whole Campus Wastewater Surveillance for SARS-CoV-2. Annals of Pub Health Rep. 2022 Feb; 6 (1): 254-255.


Stackhouse SK, Sweitzer BA, McClure PW. The effect of experimental shoulder pain on contralateral muscle force and activation. Physiother Theory Pract. 2021 Nov;37(11):1227-1234. 

McParland A, Moulton J, Brann C, Hale C, Otis Y, Ganter G. The brinker repressor system regulates injury-induced nociceptive sensitization in Drosophila melanogasterMol Pain. 2021;17:17448069211037401.

Mecum NE, Russell R, Lee J, Sullivan C, Meng ID. Optogenetic Inhibition of Nav1.8 Expressing Corneal Afferents Reduces Persistent Dry Eye Pain. Invest Ophthalmol Vis Sci. 2021 Nov 1;62(14):15.

Anthony M. Cirrincione, Cassandra  A. Reimonn, Benjamin J Harrison et al. Longitudinal RNA sequencing of skin and DRG neurons in mice with paclitaxel-induced peripheral neuropathy. 11 October 2021, PREPRINT (Version 1) available at Research Square.

Davis SM, Burman MA. Maternal separation with neonatal pain influences later-life fear conditioning and somatosenation in male and female ratsStress. 2021;24(5):504-513.

Eliza Grlickova-Duzevik, Merilla Michael, Aidan McGrath-Conwell, Peter Neufeld, Thomas M Reimonn, Derek C Molliver, Benjamin J Harrison. Members of the CUGBP Elav-Like Family of RNA-Binding Proteins are Expressed in Distinct Populations of Primary Sensory Neurons. bioRxiv 2021.07.05.451166.

Arabatzis TJ, Wakley AA, McLane VD, Canonico D, Cao L. Effects of HIV gp120 on Neuroinflammation in Immunodeficient vs. Immunocompetent States. J Neuroimmune Pharmacol. 2021 Jun;16(2):437-453. 

Payne E, Harrington K, Richard P, Brackin R, Davis R, Couture S, Liff J, Asmus F, Mutina E, Fisher A, Giuvelis D, Sannajust S, Rostama B, King T, Mattei LM, Lee JJ, Friedman ES, Bittinger K, May M, Stevenson GW. Effects of Vancomycin on Persistent Pain-Stimulated and Pain-Depressed Behaviors in Female Fischer Rats With or Without Voluntary Access to Running Wheels. J Pain. 2021 May 21;. 

Davis SM, Zuke JT, Berchulski MR, Burman MA. Amygdalar Corticotropin-Releasing Factor Signaling Is Required for Later-Life Behavioral Dysfunction Following Neonatal Pain. Front Physiol. 2021 May 11;12:660792.

Beckley JT, Pajouhesh H, Luu G, Klas S, Delwig A, Monteleone D, Zhou X, Giuvelis D, Meng ID, Yeomans DC, Hunter JC, Mulcahy JV. Antinociceptive properties of an isoform-selective inhibitor of Nav1.7 derived from saxitoxin in mouse models of pain. Pain. 2021 Apr 1;162(4):1250-1261. 

Goode DJ, Molliver DC. Regulation of Mitochondrial Function by Epac2 Contributes to Acute Inflammatory Hyperalgesia. J Neurosci. 2021 Mar 31;41(13):2883-2898. 

Nguyen LD, Nolte LG, Tan WJT, Giuvelis D, Santos-Sacchi J, Bilsky E, Ehrlich BE. Comprehensive somatosensory and neurological phenotyping of NCS1 knockout mice. Sci Rep. 2021 Jan 27;11(1):2372.


Davis SM, Burman MA. Maternal separation with neonatal pain influences later-life fear conditioning and somatosenation in male and female rats. Stress. 2020 Oct 12;:1-10.

Mecum NE, Demers D, Sullivan CE, Denis TE, Kalliel JR, Meng ID. Lacrimal gland excision in male and female mice causes ocular pain and anxiety-like behaviors. Sci Rep. 2020 Oct 14;10(1):17225.

Stevenson GW, Giuvelis D, Cormier J, Cone K, Atherton P, Krivitsky R, Warner E, St Laurent B, Dutra J, Bidlack JM, Szabò L, Polt R, Bilsky EJ. Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration. Psychopharmacology (Berl). 2020 Apr;237(4):1195-1208.

Davis SM, Rice M, Burman MA. Inflammatory neonatal pain disrupts maternal behavior and subsequent fear conditioning in a rodent model. Dev Psychobiol. 2020 Jan;62(1):88-98.

Fitzsimons LA, Brewer VL, Forrester J, Moran AM, Tucker KL. Noninvasive Electrocardiography in the Perinatal Mouse. J Vis Exp. 2020;(160):10.3791/61074. Published 2020 Jun 12.


Stefanucci A, Dimmito MP, Macedonio G, Ciarlo L, Pieretti S, Novellino E, Lei W, Barlow D, Houseknecht KL, Streicher JM, Mollica A. Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration. J Med Chem. 2019 Dec 27. 

Beauchemin M, Geguchadze R, Guntur AR, Nevola K, Le PT, Barlow D, Rue M, Vary CPH, Lary CW, Motyl KJ, Houseknecht KL. Exploring mechanisms of increased cardiovascular disease risk with antipsychotic medications: Risperidone alters the cardiac proteomic signature in mice. Pharmacol Res. 2019 Dec 23;152:104589. 

Huynh PN, Giuvelis D, Christensen S, Tucker KL, McIntosh JM. RgIA4 Accelerates Recovery from Paclitaxel-Induced Neuropathic Pain in Rats.
Mar Drugs. 2019 Dec 21;18(1). 

Mustafa R, Kreiner G, Kamińska K, Wood AJ, Kirsch J, Tucker KL, Parlato R. Targeted Depletion of Primary Cilia in Dopaminoceptive Neurons in a Preclinical Mouse Model of Huntington's Disease. Front Cell Neurosci. 2019 Dec 20;13:565. 

Eckenrode BJ, Kietrys DM, Stackhouse SK. Pain sensitivity in chronic achilles tendinopathy. Int J Sports Phys Ther. 2019 Dec;14(6):945-956.

Eaton VE, Pettit S, Elkinson A, Houseknecht KL, King TE, May M. Polymicrobial abscess following ovariectomy in a mouse. BMC Vet Res. 2019 Oct 24;15(1):364.

Stackhouse SK, Sweitzer BA, McClure PW. The effect of experimental shoulder pain on contralateral muscle force and activation. Physiother Theory Pract. 2019 Nov 7:1-8.

Loyd BJ, Burrows K, Forster JE, Stackhouse SK, Hogan C, Stevens-Lapsley JE. Reliability and precision of single frequency bioelectrical impedance assessment of lower extremity swelling following total knee arthroplasty. Physiother Theory Pract. 2019 May 29:1-7.

Knight BE, Kozlowski N, Havelin J, King T, Crocker SJ, Young EE, Baumbauer KM. TIMP-1 Attenuates the Development of Inflammatory Pain Through MMP-Dependent and Receptor-Mediated Cell Signaling Mechanisms. Front Mol Neurosci. 2019 Sep 20;12:220.

Rieder CA, Rieder J, Sannajust S, Goode D, Geguchadze R, Relich RF, Molliver DC, King TE, Vaughn J, May M. A Novel Mechanism for Zika Virus Host-Cell Binding. Viruses. 2019 Nov 28;11(12).

Sannajust S, Imbert I, Eaton V, Henderson T, Liaw L, May M, Barbe MF, King T. Females have greater susceptibility to develop ongoing pain and central sensitization in a rat model of temporomandibular joint pain. Pain. 2019 Sep;160(9):2036-2049.

Zuke JT, Rice M, Rudlong J, Paquin T, Russo E, Burman MA. The Effects of Acute Neonatal Pain on Expression of Corticotropin-Releasing Hormone and Juvenile Anxiety in a Rodent Model. eNeuro. 2019 Oct 10;6(6).

Mecum NE, Cyr D, Malon J, Demers D, Cao L, Meng ID. Evaluation of Corneal Damage After Lacrimal Gland Excision in Male and Female Mice. Invest Ophthalmol Vis Sci. 2019 Aug 1;60(10):3264-3274.

Blaszkiewicz M, Willows JW, Dubois AL, Waible S, Johnson CP, DiBello K, Lyons LL, Breeding WP, Tilbury KB, Michael M, Harrison BJ, Townsend K. Neuropathy and neural plasticity in the subcutaneous white adipose depot. BioRxiv. https://www.biorxiv.org/content/10.1101/480095v1.full

Hatta A, Kurose M, Sullivan C, Okamoto K, Fujii N, Yamamura K, Meng ID. Dry eye sensitizes cool cells to capsaicin-induced changes in activity via TRPV1. J Neurophysiol. 2019 Apr 10.

Meng ID, Barton ST, Goodney I, Russell R, Mecum NE. Progesterone Application to the Rat Forehead Produces Corneal Antinociception. Invest Ophthalmol Vis Sci. 2019 Apr 1;60(5):1706-1713.

Harrison BJ, Park JW, Gomes C, Petruska JC, Sapio MR, Iadarola MJ, Chariker JH, Rouchka EC. Detection of Differentially Expressed Cleavage Site Intervals Within 3' Untranslated Regions Using CSI-UTR Reveals Regulated Interaction Motifs. Front Genet. 2019 Mar 12;10:182.

Loyd BJ, Stackhouse S, Dayton M, Hogan C, Bade M, Stevens-Lapsley J. The relationship between lower extremity swelling, quadriceps strength, and functional performance following total knee arthroplasty. Knee. 2019 Mar 26(2):382-391.

Goode DJ, Molliver DC. Phospho-substrate profiling of Epac-dependent protein kinase C activity. Mol Cell Biochem. 2019 Feb 9.

Bove GM, Delany SP, Hobson L, et al. Manual therapy prevents onset of nociceptor activity, sensorimotor dysfunction, and neural fibrosis induced by a volitional repetitive task. Pain. 2019; 160:632-644.


Havelin J, King T. Mechanisms Underlying Bone and Joint Pain. Curr Osteoporos Rep. 2018 Dec;16(6):763-771.

Gjelsvik KJ, Follansbee TL, Ganter GK. Bone Morphogenetic Protein Glass Bottom Boat (BMP5/6/7/8) and its receptor Wishful Thinking (BMPRII) are required for injury-induced allodynia in Drosophila. Mol Pain. 2018 Jan-Dec;14:1744806918802703.

Wakley AA, Leeming R, Malon JT, Arabatzis TJ, Yuen Koh W, Cao L. Contribution of CD137L to Sensory Hypersensitivity in a Murine Model of Neuropathic Pain. eNeuro. 2018 Nov 8;5(5).

Kerr ZY, Pierpoint LA, Rosene JM. Epidemiology of Concussions in High School Boys' Ice Hockey, 2008/09 to 2016/17 School Years. Clin J Sport Med. 2018 Nov 16.

Bove GM, Delany SP, Hobson L, Cruz GE, Harris MY, Amin M, Chapelle SL, Barbe MF. Manual therapy prevents onset of nociceptor activity, sensorimotor dysfunction, and neural fibrosis induced by a volitional repetitive task. Pain. 2018 Nov 16.

Davis SM, Rice M, Rudlong J, Eaton V, King T, Burman MA. Neonatal pain and stress disrupts later-life pavlovian fear conditioning and sensory function in rats: Evidence for a two-hit model. Dev. Psychobiol. 2018 Jul;60(5):520-533.

Edwards KA, Havelin JJ, Mcintosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM. A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain. J Pain. 2018 Jun;19(6):612-625.

Cone K, Lanpher J, Kinens A, Richard P, Couture S, Brackin R, Payne E, Harrington K, Rice KC, Stevenson GW. Delta/mu opioid receptor interactions in operant conditioning assays of pain-depressed responding and drug-induced rate suppression: assessment of therapeutic index in male Sprague Dawley rats. Psychopharmacology (Berl). 2018 May;235(5):1609-1618.

Satkeviciute I, Goodwin G, Bove GM, Dilley A. Time course of ongoing activity during neuritis and following axonal transport disruption. J Neurophysiol. 2018 May 1;119(5):1993-2000.

Malon JT, Shah P, Koh WY, Cattabriga G, Li E, and Cao L. Characterizing the demographics of chronic pain patients in the state of Maine using the Maine all payer claims database. BMC Public Health. 2018. 18:810.

Cao L, Malon JT. Anti-nociceptive Role of CXCL1 in a Murine Model of Peripheral Nerve Injury-induced Neuropathic Pain. Neuroscience. 2018 Jan 6. pii: S0306-4522(17)30938-7.

Kopruszinski CM, Dos Reis RC, Gambeta E, Acco A, Rae GA, King T, Chichorro JG.Blockade of endothelin receptors reduces tumor-induced ongoing pain and evoked hypersensitivity in a rat model of facial carcinoma induced pain. Eur J Pharmacol. 2018 Jan 5;818:132-140.

Marchesseault ER, Nguyen D, Spahr L, Beals C, Razak B, Rosene JM. Head impacts and cognitive performance in men's lacrosse. Phys Sportsmed. 2018 Sep;46(3):324-300.

Rosene JM, Kerr Z. Comparison of Concussion Rates Between NCAA Division I and Division III Men's and Women's Ice Hockey Players: Response. Am J Sports Med. 2018 Apr;46(5):NP11-NP12.


Saka E, Harrison BJ, West K, Petruska JC, Rouchka EC. Framework for reanalysis of publicly available Affymetrix® GeneChip® data sets based on functional regions of interest. BMC Genomics. 2017 Dec 6;18(Suppl 10):875. 

Motyl KJ, Beauchemin M, Barlow D, Le PT, Nagano K, Treyball A, Contractor A, Baron R, Rosen CJ, Houseknecht KL. A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice. Bone. 2017 Oct;103:168-176. 

Carlson LA, Lawrence MA, Kenefick RW. Hydration Status and Thermoregulatory Responses in Drivers During Competitive Racing. J Strength Cond Res. 2017 Oct 7. [Epub ahead of print]

Govea RM, Barbe MF, Bove GM. Group IV nociceptors develop axonal chemical sensitivity during neuritis and following treatment of the sciatic nerve with vinblastine. J Neurophysiol. 2017 Oct 1;118(4):2103-2109.

McLane VD, Bergquist I, Cormier J, Barlow DJ, Houseknecht KL, Bilsky EJ, Cao L. Long-term morphine delivery via slow release morphine pellets or osmotic pumps: Plasma concentration, analgesia, and naloxone-precipitated withdrawal. Life Sci. 2017 Sep 15;185:1-7. 

Follansbee TL, Gjelsvik KJ, Brann CL, McParland AL, Longhurst CA, Galko MJ, Ganter GK. Drosophila Nociceptive Sensitization Requires BMP Signaling via the Canonical SMAD Pathway. J Neurosci. 2017 Aug 30;37(35):8524-8533. 

Cormier J, Cone K, Lanpher J, Kinens A, Henderson T, Liaw L, Bilsky EJ, King T, Rosen CJ, Stevenson GW. Exercise reverses pain-related weight asymmetry and differentially modulates trabecular bone microarchitecture in a rat model of osteoarthritis. Life Sci. 2017 Jul 1;180:51-59. 

Xie JY, De Felice M, Kopruszinski CM, Eyde N, LaVigne J, Remeniuk B, Hernandez P, Yue X, Goshima N, Ossipov M, King T, Streicher JM, Navratilova E, Dodick D, Rosen H, Roberts E, Porreca F. Kappa opioid receptor antagonists: A possible new class of therapeutics for migraine prevention. Cephalalgia. 2017 Jul;37(8):780-794. 

Carlson LA, Fowler C, Lawrence MA. Agility and Vertical Jump Performances Are Impacted by Acute Cool Exposure. J Strength Cond Res. 2017 Jul 8. [Epub ahead of print]

Allen J, Imbert I, Havelin J, Henderson T, Stevenson G, Liaw L, King T. Effects of Treadmill Exercise on Advanced Osteoarthritis Pain in Rats. Arthritis Rheumatol. 2017 Jul;69(7):1407-1417. 

Dzieweczynski TL, GreaneyNE, Portrais KB, and Stevens MA. I remember you: female Siamese fighting fish recognize prior social partners. Behaviour. 2017. 154: 19 – 35.

Dzieweczynski TL, Kane JL. The bachelorette: Female Siamese fighting fish avoid males exposed to an estrogen mimic. Behavioural Processes. July 2017. 140: 169-173.

Lei W, Mullen N, McCarthy S, Brann C, Richard P, Cormier J, Edwards K, Bilsky EJ, Streicher JM. Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain. J Biol Chem. 2017 Jun 23;292(25):10414-10428. 

Bove GM, Chapelle SL, Hanlon KE, Diamond MP, Mokler DJ. Attenuation of postoperative adhesions using a modeled manual therapy. PLoS One. 2017 Jun 2;12(6): e0178407.

Lawrence MA, Leib DJ, Ostrowski SJ, Carlson LA. Nonlinear Analysis of an Unstable Bench Press Bar Path and Muscle Activation. J Strength Cond Res. 2017 May;31(5):1206-1211.

Carlson LA, Lawrence MA, LeCavalier K, Koch AJ. Salivary Lymphocyte Responses Following Acute Anaerobic Exercise in a Cool Environment. J Strength Cond Res. 2017 May;31(5):1236-1240.

Bove GM, Chapelle SL, Boyle E, Mokler DJ, Hartvigsen J. A Novel Method for Evaluating Postoperative Adhesions in Rats. J Invest Surg. 2017 Apr;30(2):88-94.

Ostrowski SJ, Carlson LA, Lawrence MA. Effect of an Unstable Load on Primary and Stabilizing Muscles During the Bench Press. J Strength Cond Res. 2017 Feb;31(2):430-434.

Rosene JM, Raksnis B, Silva B, Woefel T, Visich PS, Dompier TP, Kerr ZY. Comparison of Concussion Rates Between NCAA Division I and Division III Men's and Women's Ice Hockey Players. Am J Sports Med. 2017 Sep;45(11):2622-2629.


Malon JT, Cao L. Preparation of Primary Mixed Glial Cultures from Adult Mouse Spinal Cord Tissue. J. Vis. Exp. 2016 (117), e54801.

Hitomi S, Kross K, Kurose M, Porreca F, Meng ID. Activation of dura-sensitive trigeminal neurons and increased c-Fos protein induced by morphine withdrawal in the rostral ventromedial medulla. Cephalalgia. 2016 May 6. pii: 0333102416648655.

Dzieweczynski TL, and LaMonica HJ. Court Like You Mean It: Male Siamese Fighting Fish are Less Attentive to Courting Males that Have Been Exposed to an Estrogen Mimic. Ethology. 15 November 2016. 122: 991–998.

Gazea M, Tasouri E, Heigl T, Bosch V, Tucker KL, Blaess S. Definition of a critical spatiotemporal window within which primary cilia control midbrain dopaminergic neurogenesis. Neurogenesis (Austin). 2016 Oct 20;3(1):e1248206. 

Molliver DC, Rau KK, Jankowski MP, Soneji DJ, Baumbauer KM, Koerber HR. Deletion of the murine ATP/UTP receptor P2Y2 alters mechanical and thermal response properties in polymodal cutaneous afferents. Neuroscience. 2016 Sep 22;332:223-30.

Malon JT, Cao L. Calcitonin gene-related peptide contributes to peripheral nerve injury-induced mechanical hypersensitivity through CCL5 and p38 pathways. J Neuroimmunol. 2016 Aug 15;297:68-75.

Fischer LK, McGaughy JA, Bradshaw SE, Weissner WJ, Amaral AC, Rosene DL, Mokler DJ, Fitzmaurice GM, Galler JR. Prenatal protein level impacts homing behavior in Long-Evans rat pups. Nutr Neurosci. 2016 Jun;19(5):187-95.

Verenna AA, Alexandru D, Karimi A, Brown JM, Bove GM, Daly FJ, Pastore AM, Pearson HE, Barbe MF. Dorsal Scapular Artery Variations and Relationship to the Brachial Plexus, and a Related Thoracic Outlet Syndrome Case. J Brachial Plex Peripher Nerve Inj. 2016 May 10;11(1):e21-e28.

Havelin J, Imbert I, Cormier J, Allen J, Porreca F, King T. Central Sensitization and Neuropathic Features of Ongoing Pain in a Rat Model of Advanced Osteoarthritis. J Pain. 2016 Mar;17(3):374-82.

Zhang Y, Williams DA, Zaidi SA, Yuan Y, Braithwaite A, Bilsky EJ, Dewey WL, Akbarali HI, Streicher JM, Selley DE.17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP). Modulating the Mu Opioid Receptor in a Biased Fashion. ACS Chem Neurosci. 2016 Mar 16;7(3):297-304. 

Deal AL, Erickson KJ, Shiers SI, Burman MA. Limbic system development underlies the emergence of classical fear conditioning during the third and fourth weeks of life in the rat. Behav Neurosci. 2016 Apr;130(2):212-30.

Peter CJ, Fischer LK, Kundakovic M, Garg P, Jakovcevski M, Dincer A, Amaral AC, Ginns EI, Galdzicka M, Bryce CP, Ratner C, Waber DP, Mokler DJ, Medford G, Champagne FA, Rosene DL, McGaughy JA, Sharp AJ, Galler JR, Akbarian S. DNA Methylation Signatures of Early Childhood Malnutrition Associated With Impairments in Attention and Cognition. Biol Psychiatry. 2016.

Harasawa I, Johansen JP, Fields HL, Porreca F, Meng ID. Alterations in the rostral ventromedial medulla after the selective ablation of mu-opioid receptor expressing neurons. Pain. 2016 Jan;157(1):166-73.


Amaral AC, Jakovcevski M, McGaughy JA, Calderwood SK, Mokler DJ, Rushmore RJ, Galler JR, Akbarian SA, Rosene DL. Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex. Neuroscience. 2015 Feb 12;286:79-86.

Duncan JR, Garland M, Stark RI, Myers MM, Fifer WP, Mokler DJ, Kinney HC. Prenatal nicotine exposure selectively affects nicotinic receptor expression in primary and associative visual cortices of the fetal baboon. Brain Pathol. 2015 Mar; 25(2):171-81. 

Bove GM. A non-invasive method to evaluate gastrointestinal transit behavior in rat. J Pharmacol Toxicol Methods. 2015 Jul-Aug;74:1-6. 

Motyl KJ, DeMambro VE, Barlow D, Olshan D, Nagano K, Baron R, Rosen CJ, Houseknecht KL. Propranolol Attenuates Risperidone-Induced Trabecular Bone Loss in Female Mice. Endocrinology. 2015 Jul;156(7):2374-83.

Quintner J, Bove GM, Cohen M. Comment on: A critical evaluation of the trigger point phenomenon: reply. Rheumatology (Oxford). 2015 Jun;54(6):1127-8.

McParland AL, Follansbee TL, Ganter GK. Measurement of larval activity in the Drosophila Activity Monitor. Journal of Visualized Experiments. J Vis Exp. 2015. 30;(98):e52684.

Meng ID, Barton ST, Mecum NE, Kurose M. Corneal sensitivity following lacrimal gland excision in the rat. Invest Ophthalmol Vis Sci. 2015 May;56(5):3347-54.

Remeniuk B, Sukhtankar D, Okun A, Navratilova E, Xie JY, King T, Porreca F. Behavioral and Neurochemical Analysis of Ongoing Bone Cancer Pain in Rats. Pain. 2015 Oct;156(10):1864-73.

Stevenson GW, Luginbuhl A, Dunbar C, LaVigne J, Dutra J, Atherton P, Bell B, Cone K, Giuvelis D, Polt R, Streicher JM, Bilsky EJ. The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. Pharmacol Biochem Behav. Feb 2015 28;132:49-55.

Motyl KJ, DeMambro VE, Barlow D, Olshan D, Nagano K, Baron R, Rosen CJ, Houseknecht KL. Propranolol Attenuates Risperidone-Induced Trabecular Bone Loss in Female Mice. Endocrinology. 2015 Jul;156(7):2374-83.

Quintner JL, Bove GM, Cohen ML. A critical evaluation of the trigger point phenomenon. Rheumatology (Oxford). 2015 Mar;54(3):392-9.

Fisher PW, Zhao Y, Rico MC, Massicotte VS, Wade CK, Litvin J, Bove GM, Popoff SN, Barbe MF. CCN2, substance P and tissue fibrosis are associated with sensorimotor declines in a rat model of repetitive overuse injury. J Cell Commun Signal. 2015 Mar;9(1):37-54.

Malon JT, Grlickova-Duzevik E, Vaughn J, Beaulac H, Vunk TR, Cao L. Microglial content-dependent inhibitory effects of calcitonin gene-related peptide (CGRP) on murine retroviral infection of glial cells. J Neuroimmunol. 2015 Feb 15;279:64-70.

Rosene JM, Matthews TD, Mcbride KJ, Galla A, Haun M, Mcdonald K, Gagne N, Lea J, Kasen J, Farias C. The effects of creatine supplementation on thermoregulation and isokinetic muscular performance following acute (3-day) supplementation. J Sports Med Phys Fitness. 2015 Dec;55(12):1488-96


McGaughy JA, Amaral AC, Rushmore RJ, Mokler DJ, Morgane PJ, Rosene DL, Galler JR. Prenatal malnutrition leads to deficits in attentional set shifting and decreases metabolic activity in prefrontal subregions that control executive function. Dev Neurosci. 2014; 36(6):532-41.

Caglič D, Krutein MC, Bompiani KM, Barlow DJ, Benoni G, Pelletier JC, Reitz AB, Lairson LL, Houseknecht KL, Smith GR, Dickerson TJ. Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain. J Med Chem. 2014 Feb 13;57(3):669-76.

McLane VD, Cao L, Willis CL. Morphine increases hippocampal viral load and suppresses frontal lobe CCL5 expression in the LP-BM5 AIDS model. J Neuroimmunol. 2014 Apr 15;269(1-2):44-51.

Deal AL, Erickson KJ, Bilsky EJ, Hillman SJ, Burman MA. K-12 Neuroscience education outreach program: Interactive activities for educating students about neuroscience. Journal of Undergraduate Neuroscience Education. 2014 Oct 15;13(1):A8-A20.

Burman MA, Erickson KJ, Deal AL, Jacobson RE. Contextual and Auditory Fear Conditioning Continue to Emerge During the Periweaning Period in Rats. PLOS ONE. 2014 Jun 30;9(6):e100807.

King T and Porreca F. Preclinical assessment of pain: improving models in discovery research. Current Topics in Behavioral Neurosciences. 2014. 20:101-120.

May M, Dunne DW, Brown DR, Sialoreceptor A. Binding Motif in the Mycoplasma synoviae Adhesin VlhA. PLoS One . 2014 Oct.

Draleau K, Maddula S, Slaiby A, Nutile-McMenemy N, De Leo J, Cao L. Phenotypic Identification of Spinal Cord-Infiltrating CD4+ T Lymphocytes in a Murine Model of Neuropathic Pain. J Pain Relief. 2014 Jun;Suppl 3:003.


Bove GM. Lending a hand to migraine PAIN. 154(9): 1493-1494. 2013.

Cao L, Butler MB. Involvement of microglial CD40 in murine retrovirus-induced peripheral neuropathy. The Journal of Neuroimmunology. 261(1-2):37-43, 2013.

Chapelle SL, Bove GM. Visceral massage reduces postoperative ileus in a rat model. Journal of Bodywork and Movement Therapies. 17(1): 83-88, 2013.

Davis J, Crawford K, Wierman H, Osgood W, Cavanaugh J, Smith KA, Mette S, Orff S. Mobilization of Ventilated Older Adults. Journal of Geriatric Physical Therapy. 36:1-7, 2013.

Dilley A, Richards N, Pulman KG, Bove GM. Disruption of Fast Axonal Transport in the Rat Induces Behavioral Changes Consistent With Neuropathic Pain. The Journal of Pain. 2013.

Largent-Milnes TM, Brookshire SW, Skinner DP, Hanlon KE, Giuvelis D, Yamamoto, Davis P, Campos CR, Nair P, Deekonda S, Bilsky EJ, Porreca F, Hruby VJ, Vanderah TW. Building a Better Analgesic: Multifunctional Compounds that Address Injury-induced Pathology to Enhance Efficacy and Eliminate Unwanted Side Effects. Journal of Pharmacology and Experimental Therapeutics. 2013.

Meng ID, Kurose M. The Role of Corneal Afferent Neurons in Regulating Tears under Normal and Dry Eye Conditions. Experimental Eye Research. 2013.

Stevenson GW, Fox MA. The Neuropharmacology of the age-old sedative/hypnotic, ethanol. Frontiers in Neuroscience. 7:122, 2013.

Willis CL, Camire RB, Brule SA, Ray DE. Partial recovery of the damaged rat blood-brain barrier is mediated by adherens junction complexes, extracellular matrix remodeling and macrophage infiltration following focal astrocyte loss. Neuroscience. 10(250):773-785, 2013.


Ananthan S, Saini SK, Dersch CM, Xu H, McGlinchey N, Giuvelis D, Bilsky EJ, Rothman RB. 14-Alkoxy- and 14-Acyloxypyridomorphinans: μ Agonist/δ Antagonist Opioid Analgesics with Diminished Tolerance and Dependence Side Effects. J Med Chem. 55(19):8350-63, 2012.

Bayron JA, Deveau AM, Stubbs JM. Conformational Analysis of 6α- and 6β-Naltrexol and Derivatives and Relationship to Opioid Receptor Affinity. J Chem Inf Model. 2012.

Bove GM. Weaving a mat of fascia research. J Bodyw Mov Ther. 16(2):132-3, 2012.

Bove GM, Chapelle SL. Visceral mobilization can lyse and prevent peritoneal adhesions in a rat model. J Bodyw Mov Ther. 16(1):76-82, 2012.

Cao L, Beaulac H, Eurich A. Differential lumbar spinal cord responses among wild type, CD4 knockout, and CD40 knockout mice in spinal nerve L5 transection-induced neuropathic pain. Molecular Pain. 8:88, 2012.

Cao L, Butler MB, Tan L, Draleau KS, Koh WY. Murine immunodeficiency virus-induced peripheral neuropathy and the associated cytokine responses. The Journal of Immunology. 189(7):3724-3733, 2012.

Col NF, Ochs L, Springmann V, Aragaki AK, Chlebowski RT. Metformin and breast cancer risk: a meta-analysis and critical literature review. Breast Cancer Res Treat. 135(3):639-46, 2012.

Ganter GK, Desilets JB, Davis-Knowlton JA, Panaitiu AE, Sweezy M, Sungail J, Tan LCH, Adams AM, Fisher EA, O'Brien JRM, Kincaid KM, Heinrich R. Drosophila female precopulatory behavior is modulated by ecdysteroids. Journal of Insect Physiology. 58(3): 413-419, 2012.

Kumar D, Rudolph KS, Manal KT. EMG-driven modeling approach to muscle force and joint load estimations: Case study in knee osteoarthritis. J Orthop Res. 30(3):377-83, 2012.

Li Y, Lefever MR, Muthu D, Bidlack JM, Bilsky EJ, Polt R. Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins. Future Med Chem. 4(2):205-26, 2012.

Lozano-Ondoua A, Hanlon K, Symons A, Largent-Milnes T, Havelin J, Ferland H 3rd, Chandramouli A, Owusu-Ankomah M, Nikolich-Zugich T, Bloom A, Jimenez-Andrade J, King T, Porreca F, Nelson M, Mantyh P, Vanderah T. Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. J Bone Miner Res. 2012.

Marsh SA, Davidoff AJ. Heart Smart Insulin-Like Growth Factor 1. Hypertension. 2012.

Martin DJ, Fitzmorris PE, Li B, Ayestas M, Sally EJ, Dersch CM, Rothman RB, Deveau AM. An efficient synthesis of 3-OBn-6β,14-epoxy-bridged opiates from naltrexone and identification of a related dual MOR inverse agonist/KOR agonist. Bioorg Med Chem Lett. 2012.

Meadows ES, Mitchell BD, Bolge SC, Johnston JA, Col NF. Factors associated with treatment of women with osteoporosis or osteopenia from a national survey. BMC Womens Health. 12(1):1, 2012.

Motyl KJ, Dick-de-Paula I, Maloney AE, Lotinun S, Bornstein S, de Paula FJ, Baron R, Houseknecht KL, Rosen CJ. Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. Bone. 50(2):490-8, 2012.

Robbins A, Kurose M, Winterson BJ, Meng ID. Menthol Activation of Corneal Cool Cells Induces TRPM8-Mediated Lacrimation but Not Nociceptive Responses in Rodents. Invest Ophthalmol Vis Sci. 53(11):7034-42, 2012.

Robbins A, Schmitt D, Winterson BJ, Meng ID. Chronic morphine increases fos-positive neurons after concurrent cornea and tail stimulation. Headache. 52(2):262-73, 2012.

Schuenke MD, Vleeming A, Van Hoof T, Willard FH. A description of the lumbar interfascial triangle and its relation with the lateral raphe: anatomical constituents of load transfer through the lateral margin of the thoracolumbar fascia. Journal of Anatomy. 221(6): 568-576, 2012.

Selvage D. Roles of the locus coeruleus and adrenergic receptors in brain-mediated hypothalamic-pituitary-adrenal axis responses to intracerebroventricular alcohol. Alcohol Clin Exp Res. 36(6):1084-90, 2012.

Vleeming A, Schuenke MD, Masi AT, Carreiro JE, Danneels L, Willard FH. The sacroiliac joint: an overview of its anatomy, function and potential clinical implications. J Anat. 2012.

Willard FH, Vleeming A, Schuenke MD, Danneels L, Schleip R. The thoracolumbar fascia: anatomy, function and clinical considerations. Journal of Anatomy. 221(6):507-536, 2012.

Willis CL. Imaging in vivo astrocyte/endothelial cell interactions at the blood-brain barrier. Methods Mol Biol. 814:515-29, 2012.

Yuan Y, Stevens DL, Braithwaite A, Scoggins KL, Bilsky EJ, Akbarali HI, Dewey WL, Zhang Y. 6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists. Bioorg Med Chem Lett. 22(14):4731-4, 2012.


Staiti AM, Morgane PJ, Galler JR, Grivetti JY, Bass DC, Mokler DJ. A microdialysis study of the medial prefrontal cortex of adolescent and adult rats. Neuropharmacology. 2011 Sep; 61(3):544-9.

Capek P, Zhang Y, Barlow DJ, Houseknecht KL, Smith GR, Dickerson TJ. Enhancing the Pharmacokinetic Properties of Botulinum Neurotoxin Serotype A Protease Inhibitors Through Rational Design. ACS Chem Neurosci. 2(6):288-293, 2011.

Carlson LA, Tighe SW, Kenefick RW, Dragon J, Westcott NW, Leclair RJ. Changes in transcriptional output of human peripheral blood mononuclear cells following resistance exercise. Eur J Appl Physiol. 111(12):2919-29, 2011.

Col N, Bozzuto L, Kirkegaard P, Koelewijn-van Loon M, Majeed H, Jen Ng C, Pacheco-Huergo V. Interprofessional education about shared decision making for patients in primary care settings. J Interprof Care. 25(6):409-15, 2011.

Cuttler AS, LeClair RJ, Stohn JP, Wang Q, Sorenson CM, Liaw L, Lindner V. Characterization of Pdgfrb-Cre transgenic mice reveals reduction of ROSA26 reporter activity in remodeling arteries. Genesis.  49(8):673-80, 2011.

De Felice M, Sanoja R, Wang R, Vera-Portocarrero L, Oyarzo J, King T, Ossipov MH, Vanderah TW, Lai J, Dussor GO, Fields HL, Price TJ, Porreca F. Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain. Pain. 152(12):2701-9, 2011.

DeNinno MP, Wright SW, Visser MS, Etienne JB, Moore DE, Olson TV, Rocke BN, Andrews MP, Zarbo C, Millham ML, Boscoe BP, Boyer DD, Doran SD, Houseknecht KL. 1,5-Substituted nipecotic amides: selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability. Bioorg Med Chem Lett. 21(10):3095-8, 2011.

Ganter GK, Panaitiu AE, Desilets JB, Davis-Heim JA, Fisher EA, Tan LC, Heinrich R, Buchanan EB, Brooks KM, Kenney MT, Verde MG, Downey J, Adams AM, Grenier JS, Maddula S, Shah P, Kincaid KM, O'Brien JR. Drosophila male courtship behavior is modulated by ecdysteroids. J Insect Physiol. 57(9):1179-84, 2011.

Kesar TM, Reisman DS, Perumal R, Jancosko AM, Higginson JS, Rudolph KS, Binder-Macleod SA. Combined effects of fast treadmill walking and functional electrical stimulation on post-stroke gait. Gait Posture. 2011 Feb;33(2):309-13.

King T, Qu C, Okun A, Mercado R, Ren J, Brion T, Lai J, Porreca F. Contribution of afferent pathways to nerve injury-induced spontaneous pain and evoked hypersensitivity. Pain. 152(9):1997-2005, 2011.

Kumar D, Rudolph KS, Manal KT. EMG-driven modeling approach to muscle force and joint load estimations: Case study in knee osteoarthritis. J Orthop Res. 2011 Sep 7. [Epub ahead of print]

Liu P, Okun A, Ren J, Guo RC, Ossipov MH, Xie J, King T, Porreca F. Ongoing pain in the MIA model of osteoarthritis. Neurosci Lett. 493(3):72-5, 2011.

Lowery JJ, Raymond TJ, Giuvelis D, Bidlack JM, Polt R, Bilsky EJ. In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice. J Pharmacol Exp Ther.  336(3):767-78, 2011.

Lund GC, Edwards G, Medlin B, Keller D, Beck B, Carreiro JE. Osteopathic manipulative treatment for the treatment of hospitalized premature infants with nipple feeding dysfunction. J Am Osteopath Assoc. 111(1):44-8, 2011.

Mellor KM, Bell JR, Wendt IR, Davidoff AJ, Ritchie RH, Delbridge LM. Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²⁺ handling in vitro. PLoS One. 6(9):e25204, 2011.

Meng ID, Dodick D, Ossipov MH, Porreca F. Pathophysiology of medication overuse headache: insights and hypotheses from preclinical studies. Cephalalgia. 31(7):851-60, 2011.

Missmer SA, Bove GM. A pilot study of the prevalence of leg pain among women with endometriosis. J Bodyw Mov Ther. 15(3):304-8, 2011

Motyl KJ, Dick-de-Paula I, Maloney AE, Lotinun S, Bornstein S, de Paula FJ, Baron R, Houseknecht KL, Rosen CJ. Trabecular bone loss after administration of the second-generation antipsychotic risperidone is independent of weight gain. Bone. Aug 11,2011.

Okun A, DeFelice M, Eyde N, Ren J, Mercado R, King T, Porreca F. Transient inflammation-induced ongoing pain is driven by TRPV1 sensitive afferents. Mol Pain. 7:4, 2011.

Qu C, King T, Okun A, Lai J, Fields HL, Porreca F. Lesion of the rostral anterior cingulate cortex eliminates the aversiveness of spontaneous neuropathic pain following partial or complete axotomy. Pain. 152(7):1641-8, 2011.

Reynolds J, Bilsky EJ, Meng ID. Selective ablation of mu-opioid receptor expressing neurons in the rostral ventromedial medulla attenuates stress-induced mechanical hypersensitivity. Life Sci. 89(9-10):313-9,2011.

Robbins A, Schmitt D, Winterson BJ, Meng ID. Chronic Morphine Increases Fos-Positive Neurons After Concurrent Cornea and Tail Stimulation. Headache. Sep 19, 2011.
Stacey D, Bennett CL, Barry MJ, Col NF, Eden KB, Holmes-Rovner M, Llewellyn-Thomas H, Lyddiatt A, Légaré F, Thomson R. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev. (10), 2011.

Staiti AM, Morgane PJ, Galler JR, Grivetti JY, Bass DC, Mokler DJ. A microdialysis study of the medial prefrontal cortex of adolescent and adult rats. Neuropharmacology. 61(3):544-9, 2011.
Stevenson GW, Mercer H, Cormier J, Dunbar C, Benoit L, Adams C, Jezierski J, Luginbuhl A, Bilsky EJ. Monosodium iodoacetate-induced osteoarthritis produces pain-depressed wheel running in rats: implications for preclinical behavioral assessment of chronic pain. Pharmacol Biochem Behav. 98(1):35-42, 2011.
Sukhtankar D, Okun A, Chandramouli A, Nelson MA, Vanderah TW, Cress AE, Porreca F, King T. Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain. Mol Pain. (7):81, 2011.

Torres TP, Fujimoto Y, Donahue EP, Printz RL, Houseknecht KL, Treadway JL, Shiota M. Defective glycogenesis contributes toward the inability to suppress hepatic glucose production in response to hyperglycemia and hyperinsulinemia in zucker diabetic fatty rats. Diabetes. 60(9):2225-33, 2011.

Tyrell CM, Roos MA, Rudolph KS, Reisman DS. Influence of systematic increases in treadmill walking speed on gait kinematics after stroke. Phys Ther. 2011 Mar;91(3):392-403.

Vera-Portocarrero LP, Ossipov MH, Lai J, King T, Porreca F. Descending facilitatory pathways from the rostroventromedial medulla mediate naloxone-precipitated withdrawal in morphine-dependent rats. J Pain. 12(6):667-76, 2011.

Whedon JM, Bove GM, Davis MA. Critique of review of deaths after chiropractic, 5. Int J Clin Pract. 65(1):105, 2011.

Willis CL. Glia-induced reversible disruption of blood-brain barrier integrity and neuropathological response of the neurovascular unit. Toxicol Pathol. 39(1):172-85, 2011.

Yeomans L, Muthu D, Lowery JJ, Martinez HN, Abrell L, Lin G, Strom K, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Phosphorylation of enkephalins: NMR and CD studies in aqueous and membrane-mimicking environments. Chem Biol Drug Des. 78(5):749-56, 2011.


Duncan JR, Paterson DS, Hoffman JM, Mokler DJ, Borenstein NS, Belliveau RA, Krous HF, Haas EA, Stanley C, Nattie EE, Trachtenberg FL, Kinney HC. Brainstem serotonergic deficiency in sudden infant death syndrome. JAMA. 2010 Feb 3;303(5):430-7. 

Bilsky EJ, Giuvelis D, Osborn MD, Dersch CM, Xu H, Rothman RB. In vitro and in vivo assessment of mu opioid receptor constitutive activity. Methods Enzymol. 2010;484:413-43.

Bove GM, Dilley A. The conundrum of sensitization when recording from nociceptors. J Neurosci Methods. 188(2):213-18, 2010.

Burman MA, Hamilton, K.L, Gewirtz, JC. The role of corticosterone in trace and delay conditioned fear-potentiated startle in rats. Behavioral Neuroscience. 24(2):294-9, 2010.

De Felice M, Ossipov MH, Wang R, Dussor G, Lai J, Meng ID, Chichorro J, Andrews JS, Rakhit S, Maddaford S, Dodick D, Porrca F. Triptan-induced enhancement of neuronal nitric oxide synthase in trigeminal ganglion dural afferents underlies increased responsiveness to potential migraine triggers. Brain. July 13, 2010.

De Felice M, Ossipov MH, Wang R, Lai J, Chichorro J, Meng I, Dodick DW, Vanderah TW, Dussor G, Porreca F. Triptan-induced latent sensitization: a possible basis for medication overuse headache. Ann Nuerol. 67(3):325-37, 2010.

Duncan JR, Paterson DS, Hoffman JM, Mokler DJ, Borenstein NS, Belliveau RA, Krous HF, Haas EA, Stanley C, Nattie EE, Trachtenberg FL, Kinney JC. Brainstem serotonergic deficiency in sudden infant death syndrome. JAMA. 303(5):430-7, 2010.

Foster JA, Burman MA. Evidence for hippocampus-dependent contextual learning at postnatal day 17 in the rat. Learning and Memory. 17(5):259-66, 2010.

Hirata H, Meng ID. Cold-sensitive corneal afferents respond to a variety of ocular stimuli central to tear production: implications for dry eye disease. Invest Opthalmol Vis Sci. 51(8):3969-76, 2010.

Larkin JW, Binks SL, Li Y, Selvage D. The role of oestradiol in sexually dimorphic hypothalamic-pituitary-adrena axis responses to intracerebroventricular ethanol administration in the rat. J Neuroendocrinol. 2010 Jan;22(1):24-32.

Lin L, Lee VM, Wang Y, Lin JS, Sock E, Wegner M, Lei L. Sox11 regulates survival and axonal growth of embryonic sensory neurons. Dev Dyn. 2010 Nov 29.

Lowery JJ, Raymond TJ, Giuvelis D, Bidlack JM, Polt R, Bilsky EJ. In vivo characterization of MMP-2200, a mixed delta/mu opioid agonist, in mice. J Pharmacol Exp Ther. 2010 Nov 30.

Lund, G, and Carreiro, JE. Characteristics of Pediatric Patients Seen in Medical School-Based Osteopathic Manipulative Medicine Clinics. JAOA. 110(7): 376-80, 2010.

Mellor KM, Ritchie RH, Davidoff AJ, Delbridge LM. Elevated dietary sugar and the heart: experimental models and myocardial remodeling. Can J Physiol Pharmacol. 88(5):525-40, 2010.

Negus, SS, Bilsky EJ, Do Carmo GP, Stevenson GW. Rationale and methods for assessment of pain-depressed behavior in preclinical assays of pain and analgesia. Methods Mol Biol. 617:79-91, 2010.

Okada-Ogawa A, Kurose M, Meng ID. Attenuation of cannabinoid-induced inhibition of medullary dorsal horn neurons by a kappa-opioid receptor antagonist. Brain Res. 2010 Nov 4;1359:81-9.

Osborn MD, Lowery JJ, Skorput AG, Giuvelis D, Bilsky EJ. In vivo characterization of the opioid antagonist nalmefene in mice. Life Sciences. 86(15-16):624-30, 2010.

Sally EJ, Xu H, Dersch CM, Hsin LW, Chang LT, Prisinzano TE, Simpson DS, Giuvelis D, Rice KC, Jacobson AE, Cheng K, Bilsky EJ, Rothman RB. Identification of a novel “almost neutral” micro-opioid receptor antagonist in CHO cells expressing the cloned human mu-opioid receptor. Synapse. 64(4):280-8, 2010.

Steele KM, Viola J, Burns E, Carreiro JE. Brief report of a clinical trial on the duration of middle ear effusion in young children using a standardized osteopathic manipulative medicine protocol. J Am Osteopath Assoc. 110(5):278-84, 2010.


Bove GM. Focal nerve inflammation induces neuronal signs consistent with symptoms of early complex regional pain syndromes. Exp Neurol. 219(1):223-27, 2009.

Bove GM, Weissner W, Barbe MF. Long lasting recruitment of immune cells and altered epi-perineurial thickness in focal nerve inflammation induced by complete Freund’s adjuvant. J Neuroimmunol. 213(1-2):26-30, 2009.

Cao L, Palmer CD, Malon JT, De Leo JA. Critical role of microglial CD40 in the maintenance of mechanical hypersensitivity in a murine model of neuropathic pain. Euro J Immunol. 39(12):3562-69, 2009.

Cao L, Tanga FY, Deleo JA. The contributing role of CD14 in toll-like receptor 4 dependent neuropathic pain. Neuroscience. 158(2):896-903, 2009.

Davis CM, Stevenson GW, Cañadas F, Ullrich T, Ric KC, Riley AL. Discriminative stimulus properties of naloxone in Long-Evans rats: assessment with the conditioned taste aversion baseline of drug discrimination learning. Psychopharmacology (Berl). 203(2):421-9, 2009.

Keyari CM, Knapp BI, Bidlack JM, Lowery J, Bilsky EJ, Polt R. Glycosyl-enkephalins: synthesis and binding at the mu, delta & kappa opioid receptors. Antinociception in mice. Adv Exp Med Biol. 611:495-6, 2009.

McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP. Occluding oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. J Neurochem. 110(1):58-71, 2009.

Mokler DJ, Dugal JR, Hoffman JM, Morgane PJ. Functional interrelations between nucleus raphé medianus: a dual probe microdialysis study of glutamate-stimulated serotonin release. Brain Res Bull. 78(4-5):132-8, 2009.

Ogawa A, Meng ID. Differential effects of the cannabinoid receptor agonist, WIN 55,212-2, on lamina I and lamina V spinal trigeminal nucleus caudalis neurons. Pain. 141(3):269-75, 2009.

Okada-Ogaway A, Porreca F, Meng ID. Sustained morphine-induced sensitization and loss of diffuse noxious inhibitory controls in dura-sensitive medullary dorsal horn neurons. J Neurosci. 29(50):15828-35, 2009.

Pelotte AL, Smith RM, Ayestas M, Dersch CM, Bilsky EJ, Rothman RB, Deveau AM. Design, synthesis, and characterization of 6beta-naltrexol analogs, and their selectivity for in vitro opioid receptor subtypes. Bloorg Med Chem Lett. 19(10):2811-14, 2009.

Pereira Do Carmo G, Stevenson GW, Carlezon WA, Negus SS. Effects of pain- and analgesia-related manipulations on intracranial self-stimulation in rats: further studies on pain-depressed behavior. Pain. 144(1-2):170-7, 2009.

Ren J, Davidoff AJ, Ingwall JS. Creatine kinase inhibitor iodoacetamide antagonizes calcium-stimulated intropoy in cardiomyocytes. Clin Exp Pharmacol Physiol. 36(2):141-5, 2009.

Stevenson GW, Cormier J, Mercer H, Adams C, Dunbar C, Negus SS, Bilsky EJ. Targeting pain-depressed behaviors in preclinical assays of pain and analgesia: drug effects on acetic acid-depressed locomotor activity in ICR mice. Life Sci. 85(7-8):309-15, 2009.

Yancey-Wrona JE, Raymond TJ, Mercer HK, Sadée W, Bilsky EJ. 6beta-naltrexol preferentially antagonizes opioid effects on gastrointestinal transit compared to antinociception in mice. Life Sci. 85(11-12):413-20, 2009.


Binks AP, Cunningham VJ, Adams L, Banzett RB. Gray matter blood flow change is unevenly distributed during moderate isocapnic hypoxia in humans. J Appl Physiol. 104(1):212-17, 2008.

Bove GM. Epi-perineurial anatomy, innervation, and axonal nociceptive mechanisms. J Bodyw Mov Ther. 12(3):185-90, 2008.

Davis MA, Bove GM. The chiropractic healer. J Manipulative Physiol Ther. 31(4):323-27, 2008.

Dilley A, Bove GM. Disruption of axoplasmic transport induces mechanical sensitivity in intact rat C-fibre nociceptor axons. J Physiol. 586(2):593-604, 2008.

Dilley A, Bove GM. Resolution of inflammation-induced axonal mechanical sensitivity and conduction slowing in C-fiber nociceptors. J Pain. 9(2):185-92, 2008.

Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptides MMP2200 in rhesus monkeys. J Pharmacol Exp Ther. 326(3):939-48, 2008.

Dreyfuss P, Snyder BD, Park K, Willard F, Carreiro J, Bogduk N. The ability of single site, single depth sacral lateral branch blocks to anesthetize the sacroiliac joint complex. Pain Med. 9(7):884-50, 2008.

Lebeche D, Davidoff AJ, Hajjar RJ. Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy. Nat Clin Pract Cardiovasc Med. 5(11):715-24, 2008.

LeClair RJ, Wang Q, Benson MA, Prudovsky I, Lindner V. Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol. 28(7):1332-38, 2008.

Negas SS, Schrode K, Stevenson GW. Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability. Exp Clin Psychopharmacol. 16(5):386-99, 2008.

Pomykala M, McElhinney B, Beck BL, Carreiro JE. Patient perception of osteopathic manipulative treatment in a hospitalized setting: a survey-based study. J Am Osteopath Assoc. 108(11):665-8, 2008.

Yin W, Willard F, Dixon T, Bogduk N. Ventral innervation of the lateral C1-C2 joint: an anatomical study. Pain Med. 9(8):1022-29, 2008.